2-Amino-5-fluoroterephthalicaciddimethylester

Base Information

Chemical Name:2-Amino-5-fluoroterephthalicaciddimethylester
CAS No.:5292-49-9
Molecular Formula:C10H10FNO4
Molecular Weight:227.19
Hs Code.:2922499990
Mol file:5292-49-9.mol

Synonyms:2-amino-5-chloroterephthalic acid dimethyl ester;2-Amino-5-chlorterephthalsaeuredimethylester;Dimethyl 2-amino-5-chloroterephthalate;dimethyl 2-amino-5-fluoro-1,4-benzenedicarboxylate;2-Amino-5-fluor-terephthalsaeure-dimethylester;dimethyl 2-amino-5-chloro-1,4-benzenedicarboxylate;2-amino-5-fluoro-terephthalic acid dimethyl ester;

Suppliers and Price of 2-Amino-5-fluoroterephthalicaciddimethylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Amino-5-fluoroterephthalicaciddimethylester

Chemical Property:

Boiling Point:371.2±42.0 °C(Predicted)
PKA:1.14±0.10(Predicted)
PSA：78.62000
Density:1.323±0.06 g/cm3(Predicted)
LogP:1.56230

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Amino-5-fluoroterephthalicaciddimethylester

There total 3 articles about 2-Amino-5-fluoroterephthalicaciddimethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 5292-48-8
2-fluoro-5-nitro-terephthalic acid dimethyl ester

: 5292-49-9
2-amino-5-fluoro-terephthalic acid dimethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 1h;
DOI:10.1021/jm070299x

Reference yield:

: 5292-47-7
1,4-dimethyl 2-fluorobenzene-1,4-dicarboxylate

: 5292-49-9
2-amino-5-fluoro-terephthalic acid dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / nitric acid; sulfuric acid / 0.25 h / 0 °C

2: 90 percent / H₂ / Pd/C / ethyl acetate / 1 h

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm070299x