diphenyl (2E)-3-phenyl-2-propenylphosphine oxide

Base Information

• Chemical Name: diphenyl (2E)-3-phenyl-2-propenylphosphine oxide
• CAS No.: 13303-60-1
• Molecular Formula: C₂₁H₁₉OP
• Molecular Weight: 318.355
• Mol file: 13303-60-1.mol

Synonyms:diphenyl (2E)-3-phenyl-2-propenylphosphine oxide

Chemical Property of diphenyl (2E)-3-phenyl-2-propenylphosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of diphenyl (2E)-3-phenyl-2-propenylphosphine oxide

There total 17 articles about diphenyl (2E)-3-phenyl-2-propenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

allyldiphenylphosphine oxide (4141-48-4) + benzoic acid hydrazide (613-94-5) → diphenyl (2E)-3-phenyl-2-propenylphosphine oxide (13303-60-1)

Guidance literature:

benzoic acid hydrazide; With copper(l) iodide; toluene-4-sulfonic acid; palladium dichloride; In dimethyl sulfoxide; acetonitrile; at 20 ℃; for 1h; under 760.051 Torr;

allyldiphenylphosphine oxide; In dimethyl sulfoxide; acetonitrile; at 100 ℃; for 3h; stereoselective reaction;

DOI:10.1002/chem.201304696

Reference yield: 82.0%

[(R)-1-(Diphenyl-phosphinoylmethyl)-2-methoxymethoxy-2-phenyl-ethyl]-dimethyl-phenyl-silane → diphenyl (2E)-3-phenyl-2-propenylphosphine oxide (13303-60-1)

Guidance literature:

With methanol;

DOI:10.1016/S0040-4039(97)00658-8

Reference yield: 78.0%

Cinnamyl acetate (21040-45-9) + lithium diphenylphosphide (65567-06-8,4541-02-0) → diphenyl (2E)-3-phenyl-2-propenylphosphine oxide (13303-60-1)

Guidance literature:

palladium(II) acetylacetonate; In tetrahydrofuran; at 0 - 20 ℃; for 6h;

DOI:10.1002/ejoc.200200671

upstream raw materials:

1-Phenyl-2-propen-1-ol

chloro-diphenylphosphine

(1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether

diphenylphosphinous acid methyl ester

Downstream raw materials:

tert-Butyl-diphenyl-[(1R,6R,7R,8S)-8-((2E,4E)-5-phenyl-penta-2,4-dienyl)-bicyclo[4.2.0]octa-2,4-dien-7-ylmethoxy]-silane

(1S,2R)-3-(diphenylphosphinoyl)-1-phenylpropane-1,2-diol

(1R,2S)-3-Diphenylphosphinoyl-1-phenylpropane-1,2-diol

(S)-(E)-3-Diphenylphosphinoyl-1-phenylprop-2-en-1-ol