3b-O-Benzoyl-18-b-glycyrrhetinic acid

Base Information

• Chemical Name: 3b-O-Benzoyl-18-b-glycyrrhetinic acid
• CAS No.: 5507-42-6
• Molecular Formula: C₃₇H₅₀O₅
• Molecular Weight: 574.801
• Mol file: 5507-42-6.mol

Synonyms:3b-O-Benzoyl-18-b-glycyrrhetinic acid

Chemical Property of 3b-O-Benzoyl-18-b-glycyrrhetinic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3b-O-Benzoyl-18-b-glycyrrhetinic acid

There total 4 articles about 3b-O-Benzoyl-18-b-glycyrrhetinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

enoxolone (471-53-4) + benzoic acid anhydride (93-97-0) → 3b-O-Benzoyl-18-b-glycyrrhetinic acid (5507-42-6)

Guidance literature:

With pyridine; dmap; at 20 ℃; for 6h;

Reference yield:

enoxolone (471-53-4) + benzoyl chloride (98-88-4) → 3b-O-Benzoyl-18-b-glycyrrhetinic acid (5507-42-6)

Guidance literature:

With pyridine; dmap; at 80 ℃; for 8h;

DOI:10.1080/07391102.2019.1570868

Reference yield:

enoxolone (471-53-4) + benzoic acid (65-85-0,8013-63-6) → 3b-O-Benzoyl-18-b-glycyrrhetinic acid (5507-42-6)

Guidance literature:

With pyridine; dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 100 - 130 ℃; microwave irradiation;

DOI:10.1016/j.bmc.2008.05.078

upstream raw materials:

enoxolone

benzoic acid

benzoyl chloride

benzoic acid anhydride