2-Chloro-6-methoxy-3-methylquinoline

Base Information

Chemical Name:2-Chloro-6-methoxy-3-methylquinoline
CAS No.:123990-76-1
Molecular Formula:C11H10 Cl N O
Molecular Weight:207.659
Hs Code.:2933499090
European Community (EC) Number:800-661-2
DSSTox Substance ID:DTXSID60406786
Wikidata:Q82211877
Mol file:123990-76-1.mol

Synonyms:2-chloro-6-methoxy-3-methylquinoline;123990-76-1;Quinoline, 2-chloro-6-methoxy-3-methyl-;MFCD02179792;2-CHLORO-6-METHOXY-3-METHYL-QUINOLINE;SCHEMBL1289590;DTXSID60406786;TVLTWDTZDXOKCD-UHFFFAOYSA-N;YEA99076;AKOS002663663;AB11436;AM803067;AS-64117;CS-0308632;EN300-126093;2-Chloro-6-methoxy-3-methylquinoline, AldrichCPR;1-(4-CHLOROPHENYL)-1-CYCLOHEXANECARBONITRILE,99

Suppliers and Price of 2-Chloro-6-methoxy-3-methylquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-6-methoxy-3-methylquinoline
100mg
$ 65.00

SynQuest Laboratories
2-Chloro-6-methoxy-3-methylquinoline
5 g
$ 874.00

SynQuest Laboratories
2-Chloro-6-methoxy-3-methylquinoline
1 g
$ 336.00

Sigma-Aldrich
2-Chloro-6-methoxy-3-methylquinoline Aldrich
1g
$ 201.00

Crysdot
2-Chloro-6-methoxy-3-methylquinoline 95+%
5g
$ 514.00

Crysdot
2-Chloro-6-methoxy-3-methylquinoline 95+%
10g
$ 771.00

Chemenu
2-Chloro-6-methoxy-3-methylquinoline 95%
5g
$ 485.00

Chemenu
2-Chloro-6-methoxy-3-methylquinoline 95%
10g
$ 728.00

American Custom Chemicals Corporation
2-CHLORO-6-METHOXY-3-METHYLQUINOLINE 95.00%
5MG
$ 495.54

Alichem
2-Chloro-6-methoxy-3-methylquinoline
10g
$ 828.20

Total 8 raw suppliers

Chemical Property of 2-Chloro-6-methoxy-3-methylquinoline

Chemical Property:

Vapor Pressure:0.000367mmHg at 25°C
Refractive Index:1.609
Boiling Point:328.2°Cat760mmHg
Flash Point:152.3°C
PSA：22.12000
Density:1.228g/cm³
LogP:3.20520
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:207.0450916
Heavy Atom Count:14
Complexity:200

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloro-6-methoxy-3-methylquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=CC(=C2)OC)N=C1Cl

Technology Process of 2-Chloro-6-methoxy-3-methylquinoline

There total 2 articles about 2-Chloro-6-methoxy-3-methylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 2760-31-8
N-(4-methoxyphenyl)-propanamide

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 123990-76-1
2-Chloro-6-methoxy-3-methylquinoline

Guidance literature:: With trichlorophosphate; at 75 ℃; for 4h;
DOI:10.1021/ja512112j

Reference yield:

: 104-94-9
4-methoxy-aniline

: 123990-76-1
2-Chloro-6-methoxy-3-methylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 2 h / 20 °C

2: trichlorophosphate / 4 h / 75 °C

With triethylamine; trichlorophosphate; In dichloromethane;
DOI:10.1021/ja512112j

Reference yield: 84.0%

: 179942-55-3
(4-(1H-tetrazol-5-yl)phenyl)boronic acid

: 123990-76-1
2-Chloro-6-methoxy-3-methylquinoline

: 1371588-17-8
2-(4-(1H-tetrazol-5-yl)phenyl)-6-methoxy-3-methylquinoline

Guidance literature:: (4-(1H-tetrazol-5-yl)phenyl)boronic acid; 2-Chloro-6-methoxy-3-methylquinoline; With 2-(2-methoxyethoxy)ethyl alcohol; potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; at 150 ℃; for 1.5h; Inert atmosphere; microwave;

With sodium hydroxide; In water;

With hydrogenchloride; In water; pH=4;