2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.:124215-44-7
Molecular Formula:C9H18 B Br O2
Molecular Weight:248.956
Hs Code.:2934999090
European Community (EC) Number:681-029-1
DSSTox Substance ID:DTXSID10564542
Nikkaji Number:J1.466.742C
Wikidata:Q82449270
Mol file:124215-44-7.mol

Synonyms:124215-44-7;2-(3-BROMOPROPYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;3-Bromopropylboronic acid pinacol ester;3-BROMOPROPYLBORONIC ACID, PINACOL ESTER;MFCD10567053;1,3,2-Dioxaborolane, 2-(3-bromopropyl)-4,4,5,5-tetramethyl-;CHQXFJUKMDJWHO-UHFFFAOYSA-N;SCHEMBL12055744;DTXSID10564542;AKOS016009118;AS-70910;CS-0174363;EN300-134748;H11844;J-005057

Suppliers and Price of 2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
3-Bromopropylboronic acid pinacol ester
1g
$ 337.00

TRC
3-Bromopropylboronic acid pinacol ester
500mg
$ 55.00

Sigma-Aldrich
3-Bromopropylboronic acid pinacol ester
1g
$ 45.30

Matrix Scientific
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
1g
$ 152.00

Matrix Scientific
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
5g
$ 404.00

Matrix Scientific
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
10g
$ 630.00

Crysdot
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
10g
$ 314.00

Crysdot
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
25g
$ 753.00

Biosynth Carbosynth
3-Bromopropylboronic acid pinacol ester
25 g
$ 780.00

Biosynth Carbosynth
3-Bromopropylboronic acid pinacol ester
5 g
$ 280.00

Total 27 raw suppliers

Chemical Property of 2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Refractive Index:n20/D 1.4559
Boiling Point:74-80 °C/1.1 mmHg
PSA：18.46000
Density:1.177 g/mL at 25 °C
LogP:2.86360
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
Water Solubility.:Not miscible or difficult to mix with water.
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:248.05832
Heavy Atom Count:13
Complexity:167

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Bromopropylboronic acid pinacol ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)CCCBr
Uses Used as primary and secondary intermediate for pharmaceutical.

Technology Process of 2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 9 articles about 2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 10294-34-5
boron trichloride

: 106-95-6
allyl bromide

: 124215-44-7
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: boron trichloride; allyl bromide; With triethylsilane; In hexane; at -78 - 20 ℃; for 1.5h; Inert atmosphere;

2,3-dimethyl-2,3-butane diol; In hexane; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1039/c5dt00814j

Reference yield: 75.0%

: 32121-07-6
trans 1,3-dibromoprop-1-ene

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 124215-44-7
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: tris(triphenylphosphine)rhodium(I) chloride; In diethyl ether; High Pressure; Ar; pinacolborane (2 equiv.) slowly added to a soln. of BrC3H4Br and RhCl(P(C6H5)3)3 at 20°C, placed under 13 kbar for 72 h; solvent removed (vac.), chromy. (silica gel, 80:20 heptane-ethyl acetate);
DOI:10.1039/b004275g

Reference yield: 70.0%

: 106-95-6
allyl bromide

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 124215-44-7
2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: With lithium aluminium tetrahydride; In neat (no solvent); at 110 ℃; for 3h; regioselective reaction;
DOI:10.1021/acscatal.7b04279