8-(4-Bromophenyl)-1,4-dioxaspiro[4.5]decane

Base Information

Chemical Name:8-(4-Bromophenyl)-1,4-dioxaspiro[4.5]decane
CAS No.:125962-61-0
Molecular Formula:C14H17 Br O2
Molecular Weight:297.192
Hs Code.:
DSSTox Substance ID:DTXSID30439369
Wikidata:Q82255309
Mol file:125962-61-0.mol

Synonyms:125962-61-0;8-(4-bromophenyl)-1,4-dioxaspiro[4.5]decane;8-(4-Bromophenyl)-1,4-dioxaspiro[4,5]decane;8-(4-Bromophenyl)-1,4-dioxasprio[4,5]decane;1,4-dioxaspiro[4.5]decane,8-(4-bromophenyl)-;SCHEMBL7292956;DTXSID30439369;AKOS015961414;AC-13679;BS-48705;F76212

Suppliers and Price of 8-(4-Bromophenyl)-1,4-dioxaspiro[4.5]decane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 8-(4-Bromophenyl)-1,4-dioxaspiro[4.5]decane

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.589
Boiling Point:376.9°Cat760mmHg
Flash Point:164.4°C
PSA：18.46000
Density:1.41g/cm³
LogP:3.84980
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:296.04119
Heavy Atom Count:17
Complexity:245

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCC1C3=CC=C(C=C3)Br)OCCO2

Technology Process of 8-(4-Bromophenyl)-1,4-dioxaspiro[4.5]decane

There total 4 articles about 8-(4-Bromophenyl)-1,4-dioxaspiro[4.5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 107-21-1
ethylene glycol

: 84892-43-3
4-(p-bromophenyl)-cyclohexanone

: 125962-61-0
4-(p-Bromophenyl)cyclohexanone ethylene ketal

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 10h; Heating;
DOI:10.1021/jo00086a042

Reference yield:

: 125962-60-9
8-(4-bromophenyl)-1,4-dioxaspiro[4.5]dec-7-ene

: 125962-61-0
4-(p-Bromophenyl)cyclohexanone ethylene ketal

Guidance literature:: Multi-step reaction with 3 steps

1: 85percent acetic acid / 3 h / 100 °C

2: 56 percent / H₂ / 5percent Rh/C / ethyl acetate / 6 h / 31028.9 Torr / Ambient temperature

3: 94 percent / TsOH*H₂O / benzene / 10 h / Heating

With hydrogen; toluene-4-sulfonic acid; acetic acid; Rh on carbon; In ethyl acetate; benzene;
DOI:10.1021/jo00086a042

Reference yield:

: 125962-59-6
4-Hydroxy-4-(p-bromophenyl)cyclohexanone ethylene ketal

: 125962-61-0
4-(p-Bromophenyl)cyclohexanone ethylene ketal

Guidance literature:: Multi-step reaction with 4 steps

1: KHSO₄ / chlorobenzene / 12 h / Heating

2: 85percent acetic acid / 3 h / 100 °C

3: 56 percent / H₂ / 5percent Rh/C / ethyl acetate / 6 h / 31028.9 Torr / Ambient temperature

4: 94 percent / TsOH*H₂O / benzene / 10 h / Heating

With potassium hydrogensulfate; hydrogen; toluene-4-sulfonic acid; acetic acid; Rh on carbon; In ethyl acetate; chlorobenzene; benzene;
DOI:10.1021/jo00086a042