3-Methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole

Base Information

Chemical Name:3-Methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole
CAS No.:129594-96-3
Molecular Formula:C₈H₁₄N₄O
Molecular Weight:182.225
Hs Code.:
ChEMBL ID:CHEMBL90318
DSSTox Substance ID:DTXSID70563511
Nikkaji Number:J350.687H
Mol file:129594-96-3.mol

Synonyms:129594-96-3;3-methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole;Piperazine, 1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)- (9CI);1-METHYL-3-(3-METHYL-1,2,4-OXADIAZOL-5-YL)PIPERAZINE;CHEMBL90318;DTXSID70563511;EN300-8096014

Suppliers and Price of 3-Methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole

Chemical Property:

PSA：54.19000
LogP:0.22080
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:182.11676108
Heavy Atom Count:13
Complexity:178

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NOC(=N1)C2CN(CCN2)C

Technology Process of 3-Methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole

There total 2 articles about 3-Methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89941-07-1
ethyl 2-piperazinecarboxylate

: 129594-96-3
1-Methyl-3-(3-methyl-[1,2,4]oxadiazol-5-yl)-piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH, molecular sieve 4A / 1.) THF, 60 deg C, 1 h, 2.) reflux, 1.5 h

2: diethyl ether

With 4 A molecular sieve; sodium hydride; In diethyl ether;
DOI:10.1021/jm00172a003