N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide

Base Information

Chemical Name:N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
CAS No.:129986-67-0
Molecular Formula:C22H22 N O2 P
Molecular Weight:363.396
Hs Code.:29241900
European Community (EC) Number:626-627-5
Nikkaji Number:J1.584.229F
Mol file:129986-67-0.mol

Synonyms:129986-67-0;N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide;N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide;Acetamide, N-methoxy-N-methyl-2-(triphenylphosphoranylidene)-;N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE;N-methoxy-N-methyl-2-(triphenyl-lambda5-phosphanylidene)acetamide;SCHEMBL225058;n-methoxy-n-methyl-2-(triphenylphosphoranylidene)-acetamide;DGBLSOOPDBHHRX-UHFFFAOYSA-N;MFCD00134433;AKOS017343617;CS-0362534;FT-0741679;J-005732;(N-Methoxymethylaminocarbonylmethylene)triphenylphosphorane;N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide, 98%;N-methoxy-N-methyl-2-(triphenyl-$l^{5-phosphanylidene)acetamide

Suppliers and Price of N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
100mg
$ 55.00

TRC
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
500mg
$ 100.00

SynQuest Laboratories
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
5 g
$ 224.00

SynQuest Laboratories
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
25 g
$ 680.00

Sigma-Aldrich
N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide 98%
25g
$ 409.00

Sigma-Aldrich
N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide 98%
5g
$ 98.80

Matrix Scientific
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)-acetamide
5g
$ 103.00

Matrix Scientific
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)-acetamide
25g
$ 395.00

Crysdot
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide 95+%
100g
$ 730.00

Alichem
N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
100g
$ 722.26

Total 14 raw suppliers

Chemical Property of N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide

Chemical Property:

Vapor Pressure:5.83E-10mmHg at 25°C
Melting Point:183 °C
Refractive Index:1.612
Boiling Point:495.6°C at 760 mmHg
Flash Point:253.5°C
PSA：39.35000
Density:1.18g/cm³
LogP:2.80250
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:363.13881594
Heavy Atom Count:26
Complexity:448

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C(=O)C=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)OC
Uses Reactant for:Synthesis of electron-deficient alkenes via stereoselective olefination of N-sulfonyl iminesPhosphine-catalyzed asymmetric addition reactionsCysteine-catalyzed enantioselective intramolecular Rauhut-Currier reactionWittig olefinationSynthesis of aigialomycin D, a Protein Kinase inhibitor and a potential anticancer agent

Technology Process of N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide

There total 6 articles about N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 67442-07-3
2-chloro-N-methoxy-N-methylacetamide

: 603-35-0
triphenylphosphine

: 129986-67-0
N-methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide

Guidance literature:: In acetonitrile; at 80 ℃; for 20h;

Reference yield:

: 134833-83-3
2-bromo-N-methoxy-N-methyl-acetamide

: 603-35-0
triphenylphosphine

: 129986-67-0
N-methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide

Guidance literature:: In ethyl acetate; at 20 ℃; for 16h;
DOI:10.1016/j.tet.2019.130694

Reference yield:

: 603-35-0
triphenylphosphine

: 129986-67-0
N-methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide

Guidance literature:: triphenylphosphine; 2-halo-N-methoxy-N-methylacetamide; In toluene; at 80 ℃; Inert atmosphere;

With sodium hydroxide; In dichloromethane; water; at 20 ℃; Inert atmosphere;
DOI:10.1002/ejoc.201001379