5-Ethynyl-2,3-dihydro-1-benzofuran

Base Information

Chemical Name:5-Ethynyl-2,3-dihydro-1-benzofuran
CAS No.:132464-87-0
Molecular Formula:C10H8O
Molecular Weight:144.173
Hs Code.:2932999099
DSSTox Substance ID:DTXSID10567972
Wikidata:Q82454051
Mol file:132464-87-0.mol

Synonyms:132464-87-0;5-Ethynyl-2,3-dihydrobenzofuran;5-ETHYNYL-2,3-DIHYDRO-1-BENZOFURAN;Benzofuran, 5-ethynyl-2,3-dihydro-;5-ETHYNYL-2,3-DIHYDROBENZO[B]FURAN;SCHEMBL1007547;DTXSID10567972;OERRNMOURWJLFE-UHFFFAOYSA-N;AKOS006238558;CS-0225049;EN300-1223699;A1-15179;F2147-2311

Suppliers and Price of 5-Ethynyl-2,3-dihydro-1-benzofuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Ethynyl-2,3-dihydrobenzofuran 95%
2.500g
$ 1650.00

American Custom Chemicals Corporation
5-ETHYNYL-2,3-DIHYDRO-BENZOFURAN 95.00%
5MG
$ 495.12

A1 Biochem Labs
5-Ethynyl-2,3-dihydrobenzofuran 95%
2.5 g
$ 1000.00

Total 4 raw suppliers

Chemical Property of 5-Ethynyl-2,3-dihydro-1-benzofuran

Chemical Property:

Boiling Point:239.7±29.0 °C(Predicted)
PSA：9.23000
Density:1.13±0.1 g/cm3(Predicted)
LogP:1.60280
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:144.057514874
Heavy Atom Count:11
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

5-Ethynyl-2,3-dihydrobenzofuran 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1=CC2=C(C=C1)OCC2

Technology Process of 5-Ethynyl-2,3-dihydro-1-benzofuran

There total 4 articles about 5-Ethynyl-2,3-dihydro-1-benzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2,3-Dihydro-benzofuran-5-ylethynyl)-trimethyl-silane

: 132464-87-0
5-ethynyl-2,3-dihydrobenzofuran

Guidance literature:: With potassium carbonate; In methanol; for 2h; Yield given; Ambient temperature;
DOI:10.1021/jm00108a031

Reference yield:

: 496-16-2
2.3-dihydrobenzofuran

: 132464-87-0
5-ethynyl-2,3-dihydrobenzofuran

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / ICl / acetic acid / 0.25 h / Ambient temperature

2: Ph₃P, CuI, Et₃N, palladium acetate / acetonitrile / 2 h / Ambient temperature

3: K₂CO₃ / methanol / 2 h / Ambient temperature

With copper(l) iodide; palladium diacetate; Iodine monochloride; potassium carbonate; triethylamine; triphenylphosphine; In methanol; acetic acid; acetonitrile;
DOI:10.1021/jm00108a031

Reference yield:

: 132464-84-7
5-iodo-2,3-dihydrobenzo[b]furan

: 132464-87-0
5-ethynyl-2,3-dihydrobenzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₃P, CuI, Et₃N, palladium acetate / acetonitrile / 2 h / Ambient temperature

2: K₂CO₃ / methanol / 2 h / Ambient temperature

With copper(l) iodide; palladium diacetate; potassium carbonate; triethylamine; triphenylphosphine; In methanol; acetonitrile;
DOI:10.1021/jm00108a031