Ethyl 1-benzoylpiperidine-4-carboxylate

Base Information

Chemical Name:Ethyl 1-benzoylpiperidine-4-carboxylate
CAS No.:136081-74-8
Molecular Formula:C15H19NO3
Molecular Weight:261.321
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70352846
Nikkaji Number:J780.927A
Wikidata:Q82130236
Mol file:136081-74-8.mol

Synonyms:ethyl 1-benzoylpiperidine-4-carboxylate;136081-74-8;1-Benzoyl-piperidine-4-carboxylic acid ethyl ester;1-benzoyl-piperidine-4-carboxylic acid-ethyl ester;ethyl 1-benzoyl-4-piperidinecarboxylate;1-BENZOylpiPERIDINE-4-CARBOXYLIC ACID ethyl ESTER;Maybridge3_002242;ethyl N-benzoylisonipecotate;ethyl-N-benzoylisonipecotate;ethyl 1-benzoylisonipecotate;ethyl 1-(phenylcarbonyl)piperidine-4-carboxylate;Oprea1_547318;SCHEMBL6973124;DTXSID70352846;HMS1437F20;MFCD00667804;STK179295;AKOS000277354;ethyl1-benzoylpiperidine-4-carboxylate;CS-W000135;IDI1_013629;ethyl 1-benzoyl-4-piperidine-carboxylate;Isonipecotic acid, N-benzoyl-, ethyl ester;FT-0720334;EN300-132300;AG-670/36150005

Suppliers and Price of Ethyl 1-benzoylpiperidine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl1-Benzoylpiperidine-4-carboxylate
50mg
$ 60.00

SynQuest Laboratories
Ethyl 1-benzoylpiperidine-4-carboxylate 97%
25 g
$ 192.00

SynQuest Laboratories
Ethyl 1-benzoylpiperidine-4-carboxylate 97%
10 g
$ 96.00

Crysdot
Ethyl1-benzoylpiperidine-4-carboxylate 97%
100g
$ 763.00

Apolloscientific
Ethyl1-benzoylpiperidine-4-carboxylate 97%
25g
$ 120.00

Apolloscientific
Ethyl1-benzoylpiperidine-4-carboxylate 97%
10g
$ 60.00

American Custom Chemicals Corporation
ETHYL 1-BENZOYLPIPERIDINE-4-CARBOXYLATE 95.00%
25G
$ 1352.22

American Custom Chemicals Corporation
ETHYL 1-BENZOYLPIPERIDINE-4-CARBOXYLATE 95.00%
5G
$ 895.01

Total 11 raw suppliers

Chemical Property of Ethyl 1-benzoylpiperidine-4-carboxylate

Chemical Property:

Melting Point:70-72℃
PSA：46.61000
LogP:2.03980
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:261.13649347
Heavy Atom Count:19
Complexity:315

Purity/Quality:

99.3% ^*data from raw suppliers

Ethyl1-Benzoylpiperidine-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CCN(CC1)C(=O)C2=CC=CC=C2

Technology Process of Ethyl 1-benzoylpiperidine-4-carboxylate

There total 8 articles about Ethyl 1-benzoylpiperidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1126-09-6
4-carbethoxypiperidine

: 98-88-4
benzoyl chloride

: 136081-74-8
ethyl 1-benzoyl-4-piperidine-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 20h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.5b00874

Reference yield: 91.0%

: 64-17-5
ethanol

: C₂₀H₁₅F₇N₂O₂

: 136081-74-8
ethyl 1-benzoyl-4-piperidine-carboxylate

Guidance literature:: With glycidyl methyl ether; potassium acetate; at 90 ℃; for 35h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02841

Reference yield: 81.0%

: 1126-09-6
4-carbethoxypiperidine

: 591-50-4
iodobenzene

: 201230-82-2
carbon monoxide

: 136081-74-8
ethyl 1-benzoyl-4-piperidine-carboxylate

: ethyl 1-(2-oxo-2-phenylacetyl)-4-piperidinecarboxylate

Guidance literature:: With palladium diacetate; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; at 50 ℃; for 24h; under 750.075 Torr; Pressure; chemoselective reaction; Inert atmosphere; Autoclave;
DOI:10.1007/s00706-014-1254-1