INDAN-2-YL-METHYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: INDAN-2-YL-METHYLAMINE HYDROCHLORIDE
• CAS No.: 146737-65-7
• Molecular Formula: C10H13 N
• Molecular Weight: 147.22
• Hs Code.: 2921499090
• Mol file: 146737-65-7.mol

Synonyms:1-(2,3-Dihydro-1H-inden-2-yl)methanamine;2-(Aminomethyl)indan; N-[(2,3-Dihydro-1H-inden-2-yl)methyl]amine

Chemical Property of INDAN-2-YL-METHYLAMINE HYDROCHLORIDE

Chemical Property:

• PSA: 26.02000
• LogP: 2.06040

Purity/Quality:

98%min ^*data from raw suppliers

2,3-Dihydro-1h-Inden-2-ylmethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of INDAN-2-YL-METHYLAMINE HYDROCHLORIDE

There total 11 articles about INDAN-2-YL-METHYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1H-indene-2-carbonitrile, 2,3-dihydro- (26453-01-0) → 1H-indene-2-methanamine, 2,3-dihydro (146737-65-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3h;

DOI:10.1021/jm010294e

Reference yield:

2-Carbamoylindane (175079-50-2) → 1H-indene-2-methanamine, 2,3-dihydro (146737-65-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 7h; Inert atmosphere; Cooling with ice;

Reference yield:

(2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride → 1H-indene-2-methanamine, 2,3-dihydro (146737-65-7)

Guidance literature:

With ammonia; In diethyl ether; for 0.166667h;

upstream raw materials:

2-(benzyloxycarbonylaminomethyl)indane

hydrogenchloride

N-indan-2-ylmethyl-phthalimide

1H-indene-2-carbonitrile, 2,3-dihydro-

Downstream raw materials:

N-indan-2-ylmethyl-phthalimide

C₃₆H₄₃N₃O₅

5-{2-[(4-chloro-benzenesulfonylamino)-methyl]-indan-5-yl}-5-oxo-pentanoic acid ethyl ester

4-{2-[(4-chloro-benzenesulfonylamino)-methyl]-indan-5-yl}-4-oxo-butyric acid

Refernces

• 1、 -. "AMINOMETHYL SUBSTITUTED BICYCLIC AROMATIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR". Page/Page column 106. . Retrieved 2010/11/08.
• 2、 Ksander,DeJesus,Yuan,Fink,Moskal,Carlson,Kukkola,Bilci,Wallace,Neubert,Feldman,Mogelesky,Poirier,Jeune,Steele,Wasvery,Stephan,Cahill,Webb,Navarrete,Lee,Gibson,Alexander,Sharif,Hospattankar. "Diaminoindanes as microsomal triglyceride transfer protein inhibitors". . p. 4677 - 4687. Retrieved 2007/10/03.