4-(Chloromethyl)-2-fluoro-1-methylbenzene

Base Information

Chemical Name:4-(Chloromethyl)-2-fluoro-1-methylbenzene
CAS No.:147542-00-5
Molecular Formula:C8H8 Cl F
Molecular Weight:158.6
Hs Code.:2903999090
European Community (EC) Number:851-036-6
DSSTox Substance ID:DTXSID30595232
Wikidata:Q82490207
Mol file:147542-00-5.mol

Synonyms:147542-00-5;4-(chloromethyl)-2-fluoro-1-methylbenzene;3-FLUORO-4-METHYLBENZYL CHLORIDE;3-Fluoro-4-methylbenzylchloride;Benzene, 4-(chloromethyl)-2-fluoro-1-methyl-;SCHEMBL6798814;DTXSID30595232;CDFRDDZQCBOCGF-UHFFFAOYSA-N;MFCD03701061;4-(chloromethyl)-2-fluoro-1-methyl benzene;CS-0233930;EN300-137200

Suppliers and Price of 4-(Chloromethyl)-2-fluoro-1-methylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(chloromethyl)-2-fluoro-1-methylbenzene
50mg
$ 155.00

TRC
4-(chloromethyl)-2-fluoro-1-methylbenzene
10mg
$ 45.00

American Custom Chemicals Corporation
3-FLUORO-4-METHYLBENZYL CHLORIDE 98.00%
5G
$ 1651.65

Alichem
3-Fluoro-4-methylbenzylchloride
1g
$ 1460.20

Alichem
3-Fluoro-4-methylbenzylchloride
500mg
$ 782.40

AK Scientific
4-(Chloromethyl)-2-fluoro-1-methylbenzene
10g
$ 4220.00

Total 7 raw suppliers

Chemical Property of 4-(Chloromethyl)-2-fluoro-1-methylbenzene

Chemical Property:

Vapor Pressure:0.575mmHg at 25°C
Refractive Index:1.505
Boiling Point:195.9°C at 760 mmHg
Flash Point:73.9°C
PSA：0.00000
Density:1.152g/cm³
LogP:2.87290
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:158.0298561
Heavy Atom Count:10
Complexity:105

Purity/Quality:

98%min ^*data from raw suppliers

4-(chloromethyl)-2-fluoro-1-methylbenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)CCl)F

Technology Process of 4-(Chloromethyl)-2-fluoro-1-methylbenzene

There total 5 articles about 4-(Chloromethyl)-2-fluoro-1-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 696-01-5
2-fluoro-1,4-dimethylbenzene

: 147542-00-5
4-(chloromethyl)-2-fluoro-1-methylbenzene

: 147541-99-9
2-fluoro-4-methylbenzyl chloride

: 127865-67-2
2-fluoro-1,4-dichloromethylbenzene

Guidance literature:: With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile); at 100 ℃; for 9h;
DOI:10.1016/S0022-1139(00)82933-4

Reference yield:

: 192702-79-7
(3-fluoro-4-methylphenyl)methanol

: 147542-00-5
4-(chloromethyl)-2-fluoro-1-methylbenzene

Guidance literature:: With thionyl chloride;

Reference yield:

: 89-58-7
mononitro-p-xylene

: 147542-00-5
4-(chloromethyl)-2-fluoro-1-methylbenzene

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / 85percent hydrazine hydrate / Raney-Ni / ethanol / 1 h / 90 °C

2: 1) NaNO2, HCl, NaBF4 / 1) water, 25 deg C, 1h, 2) Δ

3: SO₂Cl₂ / azobisisobutyronitrile / 9 h / 100 °C

With hydrogenchloride; sodium tetrafluoroborate; sulfuryl dichloride; hydrazine hydrate; sodium nitrite; 2,2'-azobis(isobutyronitrile); nickel; In ethanol;
DOI:10.1016/S0022-1139(00)82933-4