3-(4-METHOXYPHENYL)PROPYL BROMIDE

Base Information

• Chemical Name: 3-(4-METHOXYPHENYL)PROPYL BROMIDE
• CAS No.: 57293-19-3
• Molecular Formula: C10H13BrO
• Molecular Weight: 229.117
• Hs Code.: 2909309090
• Mol file: 57293-19-3.mol

Synonyms:3-(4-METHOXYPHENYL)PROPYL BROMIDE;1-(3-Bromopropyl)-4-methoxybenzene;3-(4-Methoxyphenyl)propyl bromide, 4-(3-Bromopropyl)anisole

Chemical Property of 3-(4-METHOXYPHENYL)PROPYL BROMIDE

Chemical Property:

• Vapor Pressure: 0.013mmHg at 25°C
• Refractive Index: n20/D 1.548
• Boiling Point: 104-106 °C/0.2 mmHg
• Flash Point: 110 °C
• PSA: 9.23000
• Density: 1.311 g/mL at 25 °C
• LogP: 3.02270
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(3-Bromopropyl)-4-methoxybenzene 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 22-34-52/53
• Safety Statements: 26-36/37/39-45-61

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-METHOXYPHENYL)PROPYL BROMIDE

There total 16 articles about 3-(4-METHOXYPHENYL)PROPYL BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-(p-methoxyphenyl)-1-propanol (5406-18-8) → 3-(4-methoxyphenyl)propyl bromide (57293-19-3)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1007/s00726-016-2263-7

Reference yield: 90.0%

Estragole (140-67-0) → 3-(4-methoxyphenyl)propyl bromide (57293-19-3)

Guidance literature:

With hydrogen bromide; acetic acid; In hexane; at 0 ℃; for 2h; Reagent/catalyst; Solvent;

DOI:10.1039/c6ob00692b

Reference yield:

sodium metabisulfite + 1-(4-methoxyphenyl)-1-propanol (5349-60-0) + sodium hydrogencarbonate (144-55-8) → 3-(4-methoxyphenyl)propyl bromide (57293-19-3)

Guidance literature:

With sulfurous dibromide; In N-methyl-acetamide; dichloromethane;

upstream raw materials:

Estragole

3-(p-methoxyphenyl)-1-propanol

1-p-toluenesulfonyloxy-3-(4-methoxyphenyl)propane

methyl 3-(4-methoxyphenyl)propionate

Downstream raw materials:

[3-(4-methoxy-phenyl)-propyl]-malonic acid

4-(4-methoxyphenyl)butanenitrile

1-[3-(4-methoxy-phenyl)-propyl]-2-oxo-cyclopentanecarboxylic acid ethyl ester

1,6-bis(4-methoxyphenyl)hexane

Refernces

• 1、 Yamashita, Yasunobu,Tanaka, Ken-ichiro,Yamakawa,Asano,Kanda, Yuki,Takafuji,Kawahara, Masahiro,Takenaga, Mitsuko,Fukunishi, Yoshifumi,Mizushima. "Chemical modification-mediated optimisation of bronchodilatory activity of mepenzolate, a muscarinic receptor antagonist with anti-inflammatory activity". supporting information. p. 3339 - 3346. Retrieved 2019/06/18.
• 2、 Do, Quang,Nguyen, Giang T.,Phillips, Robert S.. "Inhibition of tyrosine phenol-lyase by tyrosine homologues". . p. 2243 - 2251. Retrieved 2016/08/26.