1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-Pyridinecarbonitrile 3-Pyridinecarbonitrile,1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-

Base Information

Chemical Name:1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-Pyridinecarbonitrile 3-Pyridinecarbonitrile,1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-
CAS No.:54481-10-6
Molecular Formula:C10H12N2O2
Molecular Weight:192.22
Hs Code.:
Mol file:54481-10-6.mol

Synonyms:1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-Pyridinecarbonitrile 3-Pyridinecarbonitrile,1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-

Suppliers and Price of 1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-Pyridinecarbonitrile 3-Pyridinecarbonitrile,1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Hydroxy-4-methyl-2-oxo-1-propyl-1,2-dihydropyridine-3-carbonitrile 97%
5g
$ 312.00

Total 3 raw suppliers

Chemical Property of 1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-Pyridinecarbonitrile 3-Pyridinecarbonitrile,1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-

Chemical Property:

PSA：66.02000
LogP:1.14398

Purity/Quality:

99% ^*data from raw suppliers

6-Hydroxy-4-methyl-2-oxo-1-propyl-1,2-dihydropyridine-3-carbonitrile 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-Pyridinecarbonitrile 3-Pyridinecarbonitrile,1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-

There total 2 articles about 1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-Pyridinecarbonitrile 3-Pyridinecarbonitrile,1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 107-10-8,42939-71-9
propylamine

: 105-45-3
acetoacetic acid methyl ester

: 105-34-0
methyl 2-cyanoacetate

: 54481-10-6
1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-pyridinecarbonitrile

Guidance literature:: With silica gel; for 0.0333333h; microwave irradiation;
DOI:10.1007/s00706-002-0551-2

Reference yield: 31.0%

: 141-97-9
ethyl acetoacetate

: 52493-35-3
2-cyano-N-propylacetamide

: 54481-10-6
1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-pyridinecarbonitrile

Guidance literature:: With sodium hydroxide; In methanol; water; for 8h; Reflux;
DOI:10.2298/JSC180703092T

Reference yield: 61.0%

: 864131-95-3
N,N'-diphenylformamidine

: 54481-10-6
1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-pyridinecarbonitrile

: 1,1'-[4,5,6-tris(n-dodecan-1-yloxy)-1,3-phenylenebis(methylene)]bis(4-methylpyridinium) dibromide

: (5Z,5'Z)-5,5'-{[4,5,6-tris(dodecyloxy)-1,3-phenylene]bis[methylenepyridin-1-yl-4-ylidene(1Z)ethane-2,1-diylidene]}bis(4-methyl-2,6-dioxo-1-propyl-1,2,5,6-tetrahydropyridine-3-carbonitrile)

Guidance literature:: N,N'-diphenylformamidine; 1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-propyl-3-pyridinecarbonitrile; In acetic anhydride; at 20 - 90 ℃; for 0.75h;

1,1'-[4,5,6-tris(n-dodecan-1-yloxy)-1,3-phenylenebis(methylene)]bis(4-methylpyridinium) dibromide; With potassium acetate; In acetic anhydride; at 105 ℃; for 20h; Further stages.;
DOI:10.1055/s-2007-983900