4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole

Base Information

Chemical Name:4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
CAS No.:588676-51-1
Molecular Formula:C10H7Cl2NS
Molecular Weight:244.14
Hs Code.:2934100090
DSSTox Substance ID:DTXSID20366296
Wikidata:Q82151436
ChEMBL ID:CHEMBL1403337
Mol file:588676-51-1.mol

Synonyms:4-(chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole;588676-51-1;4-(CHLOROMETHYL)-2-(2-CHLOROPHENYL)THIAZOLE;MLS001011024;SCHEMBL2431805;CHEMBL1403337;DTXSID20366296;SORQUIQQZNHWIP-UHFFFAOYSA-N;HMS2623B04;BBL016836;MFCD03423388;STK435873;AKOS001061869;AB14530;SMR000353027;VS-05612;FT-0739240;4-chloromethyl-2-(2-chloro-phenyl)-thiazole;EN300-09772;Z56987684

Suppliers and Price of 4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
500mg
$ 189.00

Crysdot
4-(Chloromethyl)-2-(2-chlorophenyl)thiazole 95+%
5g
$ 564.00

Chemenu
4-(chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole 95%
10g
$ 960.00

Chemenu
4-(chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole 95%
5g
$ 600.00

ChemBridge Corporation
4-(chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole 95%
1 g
$ 185.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
500 mg
$ 150.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
250 mg
$ 85.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
2 g
$ 434.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
1 g
$ 255.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
5 g
$ 868.00

Total 5 raw suppliers

Chemical Property of 4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole

Chemical Property:

Vapor Pressure:1.04E-05mmHg at 25°C
Refractive Index:1.617
Boiling Point:382.4°C at 760 mmHg
Flash Point:185.1°C
PSA：41.13000
Density:1.378g/cm³
LogP:4.20230
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:242.9676258
Heavy Atom Count:14
Complexity:191

Purity/Quality:

98%min ^*data from raw suppliers

4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=NC(=CS2)CCl)Cl

Technology Process of 4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole

There total 5 articles about 4-(Chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 15717-17-6
2-chlorothiobenzamide

: 534-07-6
1,3-Dichloroacetone

: 588676-51-1
4-chloromethyl-2-(2-chloro-phenyl)-thiazole

Guidance literature:: In toluene; Reflux;
DOI:10.1021/jm401643m

Reference yield:

: 873-32-5
2-Chlorobenzonitrile

: 588676-51-1
4-chloromethyl-2-(2-chloro-phenyl)-thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; hydrogen sulfide; triethylamine

2: toluene / 2 h / Reflux

With pyridine; hydrogen sulfide; triethylamine; In toluene;
DOI:10.1002/ardp.200900198

Reference yield:

: 609-66-5
2-chlorobenzamide

: 588676-51-1
4-chloromethyl-2-(2-chloro-phenyl)-thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: tetraphosphorus decasulfide

2: ethanol; tetrahydrofuran / 6 h / 65 °C

With tetraphosphorus decasulfide; In tetrahydrofuran; ethanol;
DOI:10.1016/j.ejmech.2018.02.036