Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

Chemical Name:Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS No.:55536-71-5
Molecular Formula:C17H27NO4
Molecular Weight:309.4
Hs Code.:2933399090
European Community (EC) Number:625-338-1
DSSTox Substance ID:DTXSID50403466
Nikkaji Number:J1.862.330G
Wikidata:Q72470014
Mol file:55536-71-5.mol

Synonyms:55536-71-5;Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Ditert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;MFCD01882057;Di-tert-butyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate;SCHEMBL2150834;DTXSID50403466;WSWDAKKWVAVVAI-UHFFFAOYSA-N;AMY31780;1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Di-tert-butyl Ester;AKOS016014048;AS-47939;SY052983;CS-0182158;D4311;F17060;Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, 97%;2,6-Dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid di-tert-butyl ester

Suppliers and Price of Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Di-tert-butyl2,6-dimethylpyridine-3,5-dicarboxylate
500mg
$ 125.00

TCI Chemical
Di-tert-butyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate >98.0%(HPLC)(T)
5g
$ 252.00

TCI Chemical
Di-tert-butyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate >98.0%(HPLC)(T)
1g
$ 82.00

Sigma-Aldrich
Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97%
1g
$ 99.00

Crysdot
Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 95+%
10g
$ 309.00

Chem-Impex
Di-tert-butyl2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC)
1G
$ 84.00

Chem-Impex
Di-tert-butyl2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC)
100MG
$ 22.40

Chem-Impex
Di-tert-butyl2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC)
250MG
$ 44.80

Chem-Impex
Di-tert-butyl2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate,≥98%(Assaybytitration,HPLC) ≥98%(Assaybytitration,HPLC)
5G
$ 273.73

Chemenu
Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 95%
10g
$ 292.00

Total 20 raw suppliers

Chemical Property of Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

Vapor Pressure:2.75E-06mmHg at 25°C
Melting Point:142-149 °C
Refractive Index:1.484
Boiling Point:389.9 °C at 760 mmHg
PKA:3.34±0.70(Predicted)
Flash Point:189.6 °C
PSA：64.63000
Density:1.047 g/cm³
LogP:3.53990
Storage Temp.:2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:309.19400834
Heavy Atom Count:22
Complexity:494

Purity/Quality:

97% ^*data from raw suppliers

Di-tert-butyl2,6-dimethylpyridine-3,5-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(CC(=C(N1)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

Technology Process of Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

There total 4 articles about Di-tert-butyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1694-31-1
tert-butyl acetoacetate

: 55536-71-5
di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate

Guidance literature:: With ammonium acetate; sodium dodecyl-sulfate; toluene-4-sulfonic acid; for 1h; ultrasonic irradiation;
DOI:10.1055/s-2008-1042908

Reference yield: 35.0%

: 1694-31-1
tert-butyl acetoacetate

: 124-38-9,18923-20-1
carbon dioxide

: 55536-71-5
di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate

Guidance literature:: With potassium tert-butylate; ammonium chloride; ethanolamine; Selectfluor; In water; at 120 ℃; for 24h; Sealed tube; Green chemistry;
DOI:10.1039/d1gc02303a