Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3,4-dihydro-2-methyl- (9CI)

Base Information

Chemical Name:Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3,4-dihydro-2-methyl- (9CI)
CAS No.:54993-52-1
Molecular Formula:C8H10N2O
Molecular Weight:150.1778
Hs Code.:
Mol file:54993-52-1.mol

Synonyms:Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3,4-dihydro-2-methyl- (9CI);3,4-DIHYDRO-2-METHYL-PYRROLO[1,2-A]PYRAZIN-1(2H)-ONE

Suppliers and Price of Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3,4-dihydro-2-methyl- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3,4-dihydro-2-methyl- (9CI)

Chemical Property:

PSA：25.24000
LogP:0.51160

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3,4-dihydro-2-methyl- (9CI)

There total 4 articles about Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3,4-dihydro-2-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 123257-05-6
1-(2-bromoethyl)-1H-pyrrole-2-carboxylic acid methyl ester

: 74-89-5
methylamine

: 54993-52-1
2-methyl-3,4-dihydropyrrolo<1,2-a>pyrazin-1(2H)-one

Guidance literature:: In water; for 23h; Ambient temperature;

Reference yield:

: 1193-62-0
methyl Pyrrole-2-carboxylate

: 54993-52-1
2-methyl-3,4-dihydropyrrolo<1,2-a>pyrazin-1(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / PTC / 30 h / 25 °C

2: 75 percent / KI / acetonitrile / 30 h / 50 °C

With potassium iodide; In acetonitrile;

Reference yield:

: 123257-07-8
methyl 1-(cyanomethyl)pyrrole-2-carboxylate

: 54993-52-1
2-methyl-3,4-dihydropyrrolo<1,2-a>pyrazin-1(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / CoCl₂, NaBH₄ / methanol / 1 h / Ambient temperature

2: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 3 h

With sodium tetrahydroborate; sodium hydride; In methanol;