1,1'-(Methylene-di-4,1-phenylene)bis[2-hydroxy-2-methyl-1-propanone]

Base Information

• Chemical Name: 1,1'-(Methylene-di-4,1-phenylene)bis[2-hydroxy-2-methyl-1-propanone]
• CAS No.: 474510-57-1
• Molecular Formula: C21H24O4
• Molecular Weight: 340.419
• Mol file: 474510-57-1.mol

Synonyms:1,1'-(Methylene-di-4,1-phenylene)bis[2-hydroxy-2-methyl-1-propanone]

Chemical Property of 1,1'-(Methylene-di-4,1-phenylene)bis[2-hydroxy-2-methyl-1-propanone]

Chemical Property:

• Vapor Pressure: 0Pa at 25℃
• Melting Point: 91.3-92.0 °C
• Boiling Point: 525.6±50.0 °C(Predicted)
• PKA: 12.61±0.29(Predicted)
• Flash Point: 285.722oC
• PSA: 74.60000
• Density: 1.161±0.06 g/cm3(Predicted)
• LogP: 3.18460
• Water Solubility.: 9.9mg/L at 20℃

Purity/Quality:

99%min ^*data from raw suppliers

Irgacure127 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Irgacure 127 is a difunctional radical photoinitiator. It has been used as an initiator in the preparation and characterization of molecularly imprinted polymers based on thiourea receptors for nitro compound recognition.

Technology Process of 1,1'-(Methylene-di-4,1-phenylene)bis[2-hydroxy-2-methyl-1-propanone]

There total 4 articles about 1,1'-(Methylene-di-4,1-phenylene)bis[2-hydroxy-2-methyl-1-propanone] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1,1'-(methylenebis(4,1-phenylene))bis(2-methylpropan-1-one) (80067-83-0) → 2-hydroxy-1-(4-(4-(2-hydroxy-2-methylpropionyl)-benzyl)-phenyl)-2-methylpropan-1-one (474510-57-1)

Guidance literature:

With N-Bromosuccinimide; dimethyl sulfoxide; at 60 ℃; for 24h; Schlenk technique;

Reference yield:

4-isopropylthioxanthone (83846-86-0) + 2-isopropyl-9H-thioxanthen-9-one (5495-84-1) → phenyl bis(2,4,6-trimethylbenzoyl)phosphine oxide (162881-26-7) + 2-hydroxy-1-(4-(4-(2-hydroxy-2-methylpropionyl)-benzyl)-phenyl)-2-methylpropan-1-one (474510-57-1)

Guidance literature:

Reference yield:

C21H22Br2O2 → 2-hydroxy-1-(4-(4-(2-hydroxy-2-methylpropionyl)-benzyl)-phenyl)-2-methylpropan-1-one (474510-57-1)

Guidance literature:

With ethanol; at 13 ℃; for 3.5h; Temperature; Large scale;

upstream raw materials:

4-isopropylthioxanthone

2-isopropyl-9H-thioxanthen-9-one

Diphenylmethane

1,1'-(methylenebis(4,1-phenylene))bis(2-methylpropan-1-one)

Downstream raw materials:

type I