2-NITRO-4-METHOXYCARBONYL BENZOIC ACID

Base Information

• Chemical Name: 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID
• CAS No.: 55737-66-1
• Molecular Formula: C9H7NO6
• Molecular Weight: 225.158
• Hs Code.: 2918990090
• Mol file: 55737-66-1.mol

Synonyms:2-NITRO-4-METHOXYCARBONYL BENZOIC ACID;RARECHEM AL BE 0920;2-Nitroterephthalic acid 4-methyl ester, 97%

Chemical Property of 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID

Chemical Property:

• Vapor Pressure: 6.71E-07mmHg at 25°C
• Melting Point: 133-135°C
• Refractive Index: 1.589
• Boiling Point: 393.5°C at 760 mmHg
• Flash Point: 191.8°C
• PSA: 109.42000
• Density: 1.486g/cm³
• LogP: 1.60280
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Insoluble in water.

Purity/Quality:

97% ^*data from raw suppliers

4-(Methoxycarbonyl)-2-NitrobenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID

There total 5 articles about 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

methanol (67-56-1) + 2-nitroterephthalic acid (610-29-7) → 2-nitro-4-methoxycarbonylbenzoic acid (55737-66-1)

Guidance literature:

With sulfuric acid; for 1.25h; Heating;

DOI:10.1021/ja9539857

Reference yield: 48.0%

2-nitroterephthalic acid (610-29-7) → 2-nitro-4-methoxycarbonylbenzoic acid (55737-66-1)

Guidance literature:

2-nitroterephthalic acid; With sulfuric acid; In methanol; for 4h; Reflux;

With sodium hydrogencarbonate; In water; pH=5 - 6;

Reference yield:

methanol (67-56-1) + 2-nitroterephthalic acid (610-29-7) → dimethyl 2-nitroterephthalate (5292-45-5) + 2-nitro-4-methoxycarbonylbenzoic acid (55737-66-1)

Guidance literature:

With sulfuric acid;

upstream raw materials:

methanol

2-nitroterephthalic acid

Downstream raw materials:

methyl 4-(methylamino)carbonyl-3-nitrobenzoate

methyl 4-(chloromethyl)-3- nitrobenzoate

methyl 4-(hydroxymethyl)-3-nitrobenzoate

N-(4-chlorophenyl)-3-(3,6-dichlorobenzo[b]thiophene-2-carboxamido)terephthalamic acid methyl ester