4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBONYL CHLORIDE

Base Information

Chemical Name:4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBONYL CHLORIDE
CAS No.:52169-89-8
Molecular Formula:C11H8ClNO2
Molecular Weight:221.64
Hs Code.:2934999090
Mol file:52169-89-8.mol

Synonyms:4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBONYL CHLORIDE;5-Chlorocarbonyl-4-methyl-2-phenyl-1,3-oxazole

Suppliers and Price of 4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBONYL CHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBONYL CHLORIDE

Chemical Property:

Vapor Pressure:5.76E-05mmHg at 25°C
Refractive Index:1.562
Boiling Point:346.4°Cat760mmHg
Flash Point:163.3°C
PSA：43.10000
Density:1.278g/cm³
LogP:3.02900

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBONYL CHLORIDE

There total 3 articles about 4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79-37-8
oxalyl dichloride

: 2198-64-3,1205-02-3,90988-29-7
N-Benzoylalanine

: 52169-89-8
2-phenyl-4-methyl-oxazole-5-carbonyl chloride

Guidance literature:: In benzene; at 0 - 20 ℃; Inert atmosphere;

Reference yield:

: 2198-64-3,1205-02-3,90988-29-7
N-Benzoylalanine

: 52169-89-8
2-phenyl-4-methyl-oxazole-5-carbonyl chloride

Guidance literature:: With oxalyl dichloride; In tetrahydrofuran; at 50 ℃;
DOI:10.1016/j.bmcl.2011.09.039

Reference yield:

: 98-88-4
benzoyl chloride

: 52169-89-8
2-phenyl-4-methyl-oxazole-5-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine / dichloromethane / 1.5 h / 20 °C / Reflux

2: oxalyl dichloride / tetrahydrofuran / 50 °C

With chloro-trimethyl-silane; oxalyl dichloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2011.09.039