1-Bromo-4-methoxy-2,5-dimethylbenzene

Base Information

• Chemical Name: 1-Bromo-4-methoxy-2,5-dimethylbenzene
• CAS No.: 58106-25-5
• Molecular Formula: C9H11BrO
• Molecular Weight: 215.09
• Hs Code.: 2916399090
• European Community (EC) Number: 621-374-7
• DSSTox Substance ID: DTXSID40372910
• Nikkaji Number: J738.859D
• Wikidata: Q82160880
• Mol file: 58106-25-5.mol

Synonyms:1-Bromo-4-methoxy-2,5-dimethylbenzene;58106-25-5;4-Bromo-2,5-dimethylanisole;1174893-99-2;SCHEMBL5859293;DTXSID40372910;YSSZMKUHFOKNPD-UHFFFAOYSA-N;MFCD01652198;AKOS004907335;2-Bromo-5-methoxy-1,4-dimethylbenzene;1 -bromo-4-methoxy-2,5-dimethylbenzene;AS-63270;CS-0232960;1-Bromo-4-methoxy-2,5-dimethylbenzene, 98%;EN300-129700;F87347

Chemical Property of 1-Bromo-4-methoxy-2,5-dimethylbenzene

Chemical Property:

• Vapor Pressure: 0.0352mmHg at 25°C
• Melting Point: 34-38 °C(lit.)
• Refractive Index: 1.532
• Boiling Point: 250°Cat760mmHg
• Flash Point: 110.1°C
• PSA: 9.23000
• Density: 1.326g/cm³
• LogP: 3.07450
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 213.99933
• Heavy Atom Count: 11
• Complexity: 127

Purity/Quality:

98%min ^*data from raw suppliers

1-Bromo-4-methoxy-2,5-dimethylbenzene ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1Br)C)OC

Technology Process of 1-Bromo-4-methoxy-2,5-dimethylbenzene

There total 5 articles about 1-Bromo-4-methoxy-2,5-dimethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,5-Dimethyl-anisol (1706-11-2) → 1-bromo-4-methoxy-2,5-dimethylbenzene (58106-25-5)

Guidance literature:

With benzyltrimethylazanium tribroman-2-uide; In methanol; dichloromethane; for 0.0166667h; Ambient temperature;

Reference yield: 96.0%

4-bromo-2,5-dimethyl-phenol (85223-93-4) + methyl iodide (74-88-4) → 1-bromo-4-methoxy-2,5-dimethylbenzene (58106-25-5)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 1h;

DOI:10.1021/ma011768m

Reference yield:

2,5-Dimethylphenol (95-87-4) → 1-bromo-4-methoxy-2,5-dimethylbenzene (58106-25-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / NBS / dimethylformamide / 20 °C

2: 96 percent / KOH / dimethylsulfoxide / 1 h / 20 °C

With potassium hydroxide; N-Bromosuccinimide; In dimethyl sulfoxide; N,N-dimethyl-formamide;

DOI:10.1021/ma011768m

upstream raw materials:

2,5-Dimethyl-anisol

4-bromo-2,5-dimethyl-phenol

dimethyl sulfate

methyl iodide

Downstream raw materials:

2-bromo-5-methoxyterephthalic acid

4-Methoxy-2,5-dimethyl-diphenyl-sulfid

2,5-dimethyl-4-(9-phenylanthracen-10-yl)anisole

allyl 2,5-dimethyl-4-methoxyphenyl selenide