5-Bromo-2,3-dihydro-1,4-benzodioxine

Base Information

Chemical Name:5-Bromo-2,3-dihydro-1,4-benzodioxine
CAS No.:58328-39-5
Molecular Formula:C8H7BrO2
Molecular Weight:215.046
Hs Code.:2934999090
European Community (EC) Number:681-013-4
DSSTox Substance ID:DTXSID30596264
Nikkaji Number:J3.656.030D
Wikidata:Q82491482
Mol file:58328-39-5.mol

Synonyms:58328-39-5;5-BROMO-2,3-DIHYDRO-1,4-BENZODIOXANE;5-BROMO-1,4-BENZODIOXANE;5-Bromo-2,3-dihydro-1,4-benzodioxine;5-bromo-2,3-dihydrobenzo[b][1,4]dioxine;MFCD03095029;1,4-Benzodioxin, 5-bromo-2,3-dihydro-;SCHEMBL4564550;DTXSID30596264;NGOZRIZXELGVHK-UHFFFAOYSA-N;AMY15280;AKOS015835890;5-bromo-2,3-dihydrobenzo[1,4]dioxin;BS-2086;5-Bromo-1,4-benzodioxane, AldrichCPR;5-bromo-2,3-dihydro[1,4]benzodioxine;5-bromo-2,3-dihydro[1,4]-benzodioxine;SY022072;DB-072463;CS-0114016;4-AMINO-2,6-DICHLOROPHENOLHYDROCHLORIDE;EN300-204925;A858208

Suppliers and Price of 5-Bromo-2,3-dihydro-1,4-benzodioxine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-1,4-benzodioxane
250mg
$ 120.00

SynQuest Laboratories
5-Bromo-2,3-dihydro-1,4-benzodioxane 96%
5 g
$ 1103.00

SynQuest Laboratories
5-Bromo-2,3-dihydro-1,4-benzodioxane 96%
1 g
$ 277.00

Sigma-Aldrich
5-Bromo-1,4-benzodioxane Aldrich
1g
$ 162.00

Matrix Scientific
5-Bromo-2,3-dihydro-1,4-benzodioxane
500mg
$ 775.00

Matrix Scientific
5-Bromo-2,3-dihydro-1,4-benzodioxane
1g
$ 978.00

Labseeker
5-BROMO-2,3-DIHYDRO-1,4-BENZODIOXANE 95
10g
$ 847.00

Crysdot
5-Bromo-2,3-dihydro-1,4-benzodioxane 97%
5g
$ 527.00

Chemenu
5-Bromo-2,3-dihydro-1,4-benzodioxane 97%
5g
$ 497.00

American Custom Chemicals Corporation
5-BROMO-2,3-DIHYDRO-1,4-BENZODIOXANE 95.00%
1G
$ 1158.70

Total 30 raw suppliers

Chemical Property of 5-Bromo-2,3-dihydro-1,4-benzodioxine

Chemical Property:

Vapor Pressure:0.0193mmHg at 25°C
Melting Point:55.5℃
Refractive Index:1.579
Boiling Point:260.9°Cat760mmHg
Flash Point:119.6°C
PSA：18.46000
Density:1.598g/cm³
LogP:2.22030
Storage Temp.:Room temperature.
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:213.96294
Heavy Atom Count:11
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-1,4-benzodioxane ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.;
Hazard Codes:Xn
Statements: 22
Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(O1)C=CC=C2Br
Uses 5-Bromo-1,4-benzodioxane is a reagent used in the preparation of a kinase M2 activator for cancer therapy.

Technology Process of 5-Bromo-2,3-dihydro-1,4-benzodioxine

There total 1 articles about 5-Bromo-2,3-dihydro-1,4-benzodioxine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 14381-51-2
3-bromo-1,2-dihydroxybenzene

: 106-93-4
ethylene dibromide

: 58328-39-5
5-bromo-2,3-dihydrobenzo[1,4]dioxin

Guidance literature:: With potassium fluoride; potassium carbonate; In N,N-dimethyl-formamide; at 135 ℃; for 2h; Inert atmosphere;

Reference yield: 78.0%

: 150-60-7
dibenzyl disulphide

: 58328-39-5
5-bromo-2,3-dihydrobenzo[1,4]dioxin

: 5-(benzylsulfanyl)-2,3-dihydro-1,4-benzodioxine

Guidance literature:: 5-bromo-2,3-dihydrobenzo[1,4]dioxin; With sec.-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

dibenzyl disulphide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

Reference yield: 69.0%

: 58328-39-5
5-bromo-2,3-dihydrobenzo[1,4]dioxin

: 87474-15-5
2,3-dihydro-1,4-benzodioxine-5-sulfonyl chloride

Guidance literature:: 5-bromo-2,3-dihydrobenzo[1,4]dioxin; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

With sulfur dioxide; In tetrahydrofuran; hexane; for 0.166667h;

With N-chloro-succinimide; In acetic acid; at -78 - 20 ℃; for 1.25h;