(5-(4-Methoxyphenyl)isoxazol-3-YL)methanol

Base Information

• Chemical Name: (5-(4-Methoxyphenyl)isoxazol-3-YL)methanol
• CAS No.: 58492-77-6
• Molecular Formula: C11H11NO3
• Molecular Weight: 205.213
• Hs Code.: 2934999090
• European Community (EC) Number: 621-638-1
• DSSTox Substance ID: DTXSID30586428
• Wikidata: Q82478561
• Mol file: 58492-77-6.mol

Synonyms:58492-77-6;(5-(4-METHOXYPHENYL)ISOXAZOL-3-YL)METHANOL;[5-(4-methoxyphenyl)isoxazol-3-yl]methanol;[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]methanol;F2135-0535;SCHEMBL8196656;DTXSID30586428;AMY27774;MFCD06199341;STK506075;AKOS002671657;CCG-309932;MCULE-9055145331;LS-03269;DB-000761;C16032;EN300-237846;(5-(4-METHOXYPHENYL)-3-ISOXAZOLYL)METHANOL

Chemical Property of (5-(4-Methoxyphenyl)isoxazol-3-YL)methanol

Chemical Property:

• PSA: 55.49000
• LogP: 1.84250
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 205.07389321
• Heavy Atom Count: 15
• Complexity: 192

Purity/Quality:

98%min ^*data from raw suppliers

[5-(4-methoxyphenyl)isoxazol-3-yl]methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=CC(=NO2)CO

Technology Process of (5-(4-Methoxyphenyl)isoxazol-3-YL)methanol

There total 8 articles about (5-(4-Methoxyphenyl)isoxazol-3-YL)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methyl 5-(4-methoxyphenyl)isoxazole-3-carboxylate (425609-97-8) → (5-(4-methoxyphenyl)isoxazol-3-yl)methanol (58492-77-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 50 ℃; for 5h;

DOI:10.1016/j.ejmech.2019.111635

Reference yield:

ethyl 5-(4-methoxyphenyl)isoxazole-3-carboxylate (925006-96-8) → (5-(4-methoxyphenyl)isoxazol-3-yl)methanol (58492-77-6)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; ethanol; at 0 ℃; for 4h;

DOI:10.1016/j.ejps.2010.11.010

Reference yield:

ethyl 3-(4-methoxybenzoyl)pyruvate (35322-20-4) → (5-(4-methoxyphenyl)isoxazol-3-yl)methanol (58492-77-6)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / ethanol / 6 h / Reflux

2: sodium tetrahydroborate / tetrahydrofuran; ethanol / 4 h / 0 °C

With sodium tetrahydroborate; hydroxylamine hydrochloride; In tetrahydrofuran; ethanol;

DOI:10.1016/j.ejps.2010.11.010

upstream raw materials:

ethyl 5-(4-methoxyphenyl)isoxazole-3-carboxylate

ethyl 3-(4-methoxybenzoyl)pyruvate

1-(4-methoxyphenyl)ethanone

methyl 5-(4-methoxyphenyl)isoxazole-3-carboxylate

Downstream raw materials:

3-(bromomethyl)-5-(4-methoxyphenyl)isoxazole

C₂₃H₂₅N₃O₄*ClH

C₂₄H₂₇N₅O₄*ClH

C₁₁H₉NO₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 58492-77-6 (5-(4-Methoxyphenyl)isoxazol-3-yl)methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send