Methyl 5-(3-fluorophenyl)furan-2-carboxylate

Base Information

Chemical Name:Methyl 5-(3-fluorophenyl)furan-2-carboxylate
CAS No.:54023-07-3
Molecular Formula:C12H9FO3
Molecular Weight:220.2
Hs Code.:2932190090
DSSTox Substance ID:DTXSID30459446
Wikidata:Q82283213
Mol file:54023-07-3.mol

Synonyms:54023-07-3;Methyl 5-(3-fluorophenyl)furan-2-carboxylate;5-(3-FLUOROPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER;SCHEMBL4949353;DTXSID30459446;CVEIQBUPXKHIJO-UHFFFAOYSA-N;AKOS015963812;FT-0711604

Suppliers and Price of Methyl 5-(3-fluorophenyl)furan-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-(3-FLUOROPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 499.17

Total 2 raw suppliers

Chemical Property of Methyl 5-(3-fluorophenyl)furan-2-carboxylate

Chemical Property:

Melting Point:82 °C
Boiling Point:151-153 °C(Press: 2 Torr)
PSA：39.44000
Density:1.225±0.06 g/cm3(Predicted)
LogP:2.87230
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:220.05357231
Heavy Atom Count:16
Complexity:257

Purity/Quality:

99%+ ^*data from raw suppliers

5-(3-FLUOROPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=C(O1)C2=CC(=CC=C2)F

Technology Process of Methyl 5-(3-fluorophenyl)furan-2-carboxylate

There total 5 articles about Methyl 5-(3-fluorophenyl)furan-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2527-99-3
methyl 5-bromo-2-furoate

: 768-35-4
3-fluorophenylboronic acid

: 54023-07-3
5-(3-fluorophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; Inert atmosphere; Reflux;
DOI:10.1016/j.ejmech.2020.112669

Reference yield: 52.0%

: 611-13-2
2-furoic acid methyl ester

: 1073-06-9
3-fluorobromobenzene

: 54023-07-3
5-(3-fluorophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: With potassium acetate; palladium diacetate; In N,N-dimethyl acetamide; at 130 ℃; for 20h; regioselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201101102

Reference yield: 46.0%

: 611-13-2
2-furoic acid methyl ester

: 372-19-0
meta-fluoroaniline

: 54023-07-3
5-(3-fluorophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: meta-fluoroaniline; With hydrogenchloride; sodium nitrite;

2-furoic acid methyl ester; With copper(II) chloride dihydrate; In water; acetone; at 0 - 30 ℃;
DOI:10.1134/S1070428009040125