(Pyridine-3-carbonyl)amino-acetic acid ethyl ester

Base Information

Chemical Name:(Pyridine-3-carbonyl)amino-acetic acid ethyl ester
CAS No.:54466-74-9
Molecular Formula:C10H12N2O3
Molecular Weight:208.217
Hs Code.:2933399090
DSSTox Substance ID:DTXSID30697720
Mol file:54466-74-9.mol

Synonyms:(pyridine-3-carbonyl)amino-acetic acid ethyl ester;DTXSID30697720;ETHYL 2-AMINO-3-OXO-3-(PYRIDIN-3-YL)PROPANOATE

Suppliers and Price of (Pyridine-3-carbonyl)amino-acetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL-2-(PYRIDINE-3-CARBONYLAMINO)ACETATE 95.00%
5MG
$ 500.10

Total 8 raw suppliers

Chemical Property of (Pyridine-3-carbonyl)amino-acetic acid ethyl ester

Chemical Property:

PSA：68.29000
LogP:0.76540
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:208.08479225
Heavy Atom Count:15
Complexity:243

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-2-(PYRIDINE-3-CARBONYLAMINO)ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(=O)C1=CN=CC=C1)N

Technology Process of (Pyridine-3-carbonyl)amino-acetic acid ethyl ester

There total 5 articles about (Pyridine-3-carbonyl)amino-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 10400-19-8
3-pyridinecarbonyl chloride

: 623-33-6
glycine ethyl ester hydrochloride

: 54466-74-9
N³-((ethoxycarbonyl)-methyl)nicotinamide

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 0 ℃; for 2h;
DOI:10.1021/ja00318a041

Reference yield:

: 59-67-6
nicotinic acid

: 54466-74-9
N³-((ethoxycarbonyl)-methyl)nicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂, DMF / toluene / 0.5 h / 60 - 70 °C

2: K₂CO₃ / H₂O; toluene / -5 - 5 °C

With thionyl chloride; potassium carbonate; N,N-dimethyl-formamide; In water; toluene;
DOI:10.1248/cpb.28.2045