2-Amino-6-(4-bromophenyl)-4-phenyl-1,4,5,6-tetrahydro-7h-pyrrolo[3,4-d]pyrimidin-7-one

Base Information

Chemical Name:2-Amino-6-(4-bromophenyl)-4-phenyl-1,4,5,6-tetrahydro-7h-pyrrolo[3,4-d]pyrimidin-7-one
CAS No.:76628-96-1
Molecular Formula:C₁₈H₁₅BrN₄O
Molecular Weight:383.247
Hs Code.:
NSC Number:140055
DSSTox Substance ID:DTXSID00300936

Synonyms:76628-96-1;2-Amino-6-(4-bromophenyl)-4-phenyl-5,6-dihydro-1H-pyrrolo[3,4-d]pyrimidin-7(4H)-one;NSC140055;2-amino-6-(4-bromophenyl)-4-phenyl-1,4,5,6-tetrahydro-7h-pyrrolo[3,4-d]pyrimidin-7-one;DTXSID00300936;NSC-140055

Suppliers and Price of 2-Amino-6-(4-bromophenyl)-4-phenyl-1,4,5,6-tetrahydro-7h-pyrrolo[3,4-d]pyrimidin-7-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 2-Amino-6-(4-bromophenyl)-4-phenyl-1,4,5,6-tetrahydro-7h-pyrrolo[3,4-d]pyrimidin-7-one

Chemical Property:

Vapor Pressure:7.63E-13mmHg at 25°C
Boiling Point:566.3°C at 760 mmHg
Flash Point:296.3°C
Density:1.63g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:382.04292
Heavy Atom Count:24
Complexity:574

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2=C(C(=O)N1C3=CC=C(C=C3)Br)NC(=NC2C4=CC=CC=C4)N

Technology Process of 2-Amino-6-(4-bromophenyl)-4-phenyl-1,4,5,6-tetrahydro-7h-pyrrolo[3,4-d]pyrimidin-7-one

There total 4 articles about 2-Amino-6-(4-bromophenyl)-4-phenyl-1,4,5,6-tetrahydro-7h-pyrrolo[3,4-d]pyrimidin-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 76628-94-9
1-p-bromophenyl-4-benzylidene-2,3-dioxopyrrolidine

: 113-00-8
guanidine nitrate

: 76628-96-1
2-amino-6-p-bromophenyl-4-phenyl-3,4-dihydro-5H-pyrrolo<3,4-d>pyrimidin-7-(6H)one

Guidance literature:: In ethanol; for 1h; Heating;
DOI:10.1002/jhet.5570170617

Reference yield:

: 76628-93-8
1-p-bromophenyl-4-carbethoxy-2,3-dioxopyrrolidine

: 76628-96-1
2-amino-6-p-bromophenyl-4-phenyl-3,4-dihydro-5H-pyrrolo<3,4-d>pyrimidin-7-(6H)one

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / 20percent hydrochloric acid / ethanol / 16 h / Heating

2: 64 percent / ethanol / 1 h / Heating

With hydrogenchloride; In ethanol;
DOI:10.1002/jhet.5570170617

Reference yield:

: 100-52-7
benzaldehyde

: 76628-96-1
2-amino-6-p-bromophenyl-4-phenyl-3,4-dihydro-5H-pyrrolo<3,4-d>pyrimidin-7-(6H)one

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / 20percent hydrochloric acid / ethanol / 16 h / Heating

2: 64 percent / ethanol / 1 h / Heating

With hydrogenchloride; In ethanol;
DOI:10.1002/jhet.5570170617