BOC-MET-ENKEPHALIN

Base Information

• Chemical Name: BOC-MET-ENKEPHALIN
• CAS No.: 59481-77-5
• Molecular Formula: C32H43N5O9S
• Molecular Weight: 673.788
• Mol file: 59481-77-5.mol

Synonyms:BOC-TYR-GLY-GLY-PHE-MET;BOC-TYR-GLY-GLY-PHE-MET-OH;BOC-MET-ENKEPHALIN;N-ALPHA-T-BOC-[MET5]-ENKEPHALIN;N-ALPHA-T-BOC-L-TYR-GLY-GLY-PHE-MET

Chemical Property of BOC-MET-ENKEPHALIN

Chemical Property:

• PSA: 237.56000
• LogP: 3.06490
• Storage Temp.: -15°C

Purity/Quality:

99%, ^*data from raw suppliers

Boc-Met-Enkephalin Boc-Tyr-Gly-Gly-Phe-Met-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BOC-MET-ENKEPHALIN

There total 21 articles about BOC-MET-ENKEPHALIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Boc-Tyr-Gly-Gly-Phe-Met-OTcrom (79255-49-5) → boc-Tyr-Gly-Gly-Phe-Met-OH (59481-77-5)

Guidance literature:

With propylamine; at 25 ℃; for 0.0333333h;

DOI:10.1021/jo00337a030

Reference yield: 86.0%

methyl N-tert-butoxycarbonyl-L-tyrosyldiglycyl-L-phenylalanyl-L-methioninate (60566-44-1) → boc-Tyr-Gly-Gly-Phe-Met-OH (59481-77-5) + N-<1-carboxy-2-(4-hydroxyphenyl)ethylaminocarbonyl>diglycyl-L-phenylalanyl-L-methionine

Guidance literature:

With sodium hydroxide; In acetone; for 1.5h;

DOI:10.1248/cpb.46.1672

Reference yield: 79.0%

BOC-L-Tyr-Gly-Gly-L-Phe-L-Met-CAM (98229-09-5) → boc-Tyr-Gly-Gly-Phe-Met-OH (59481-77-5)

Guidance literature:

With sodium carbonate; In water; N,N-dimethyl-formamide; for 1.5h;

DOI:10.1016/S0040-4020(01)96451-8

upstream raw materials:

(S)-2-{(S)-2-[2-(2-Amino-acetylamino)-acetylamino]-3-phenyl-propionylamino}-4-methylsulfanyl-butyric acid; hydrochloride

N-t-butyloxycarbonyl-L-tyrosine

BocTyr(2-BrZ)GlyGlyPheMetOH

BOC-L-Tyr-Gly-Gly-L-Phe-L-Met-CAM

Downstream raw materials:

met-enkephalin

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