4-Chloro-2-(4-methoxyphenyl)quinazoline

Base Information

Chemical Name:4-Chloro-2-(4-methoxyphenyl)quinazoline
CAS No.:55391-00-9
Molecular Formula:C15H11ClN2O
Molecular Weight:270.718
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50352708
Nikkaji Number:J2.866.311K
Wikidata:Q82129987
Mol file:55391-00-9.mol

Synonyms:4-chloro-2-(4-methoxyphenyl)quinazoline;55391-00-9;4-Chloro-2-(4-methoxy-phenyl)-quinazoline;MFCD03847393;F3098-8763;SCHEMBL16404325;DTXSID50352708;AKOS000200071;AB16813;4-Chloro-2-(4-methoxy-phenyl)quinazoline;CS-0453572;FT-0709334;A830620;SR-01000320460;SR-01000320460-1

Suppliers and Price of 4-Chloro-2-(4-methoxyphenyl)quinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
4-Chloro-2-(4-methoxy-phenyl)-quinazoline 97%
500mg
$ 279.00

J&W Pharmlab
4-Chloro-2-(4-methoxy-phenyl)-quinazoline 97%
5g
$ 1832.00

J&W Pharmlab
4-Chloro-2-(4-methoxy-phenyl)-quinazoline 97%
1g
$ 458.00

Crysdot
4-Chloro-2-(4-methoxyphenyl)quinazoline 95+%
1g
$ 406.00

Chemenu
4-Chloro-2-(4-methoxy-phenyl)-quinazoline 95%
1g
$ 383.00

American Custom Chemicals Corporation
4-CHLORO-2-(4-METHOXY-PHENYL)QUINAZOLINE 98.00%
5MG
$ 503.75

Alichem
4-Chloro-2-(4-methoxyphenyl)quinazoline
1g
$ 357.48

Total 8 raw suppliers

Chemical Property of 4-Chloro-2-(4-methoxyphenyl)quinazoline

Chemical Property:

Melting Point:123 °C(Solv: ethanol (64-17-5))
Boiling Point:338.9±34.0 °C(Predicted)
PKA:0.84±0.30(Predicted)
PSA：35.01000
Density:1.281±0.06 g/cm3(Predicted)
LogP:3.95880
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:270.0559907
Heavy Atom Count:19
Complexity:294

Purity/Quality:

98%min ^*data from raw suppliers

4-Chloro-2-(4-methoxy-phenyl)-quinazoline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=N2)Cl

Technology Process of 4-Chloro-2-(4-methoxyphenyl)quinazoline

There total 8 articles about 4-Chloro-2-(4-methoxyphenyl)quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1152-07-4
2-(4-methoxyphenyl)-3H-quinazolin-4-one

: 55391-00-9
2-(p-methoxyphenyl)-4-chloroquinazoline

Guidance literature:: With trichlorophosphate; at 20 ℃; Reflux;
DOI:10.1016/j.ejmech.2017.08.020

Reference yield:

: 28144-70-9,88-68-6
anthranilic acid amide

: 55391-00-9
2-(p-methoxyphenyl)-4-chloroquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; iodine / N,N-dimethyl-formamide / 70 - 90 °C

2: trichlorophosphate; N,N-dimethyl-aniline / 6 h / Reflux

With iodine; potassium carbonate; N,N-dimethyl-aniline; trichlorophosphate; In N,N-dimethyl-formamide; 1: |Niementowski Quinazolone Synthesis;
DOI:10.1002/ardp.201400337

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 55391-00-9
2-(p-methoxyphenyl)-4-chloroquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; iodine / N,N-dimethyl-formamide / 70 - 90 °C

2: trichlorophosphate; N,N-dimethyl-aniline / 6 h / Reflux

With iodine; potassium carbonate; N,N-dimethyl-aniline; trichlorophosphate; In N,N-dimethyl-formamide; 1: |Niementowski Quinazolone Synthesis;
DOI:10.1002/ardp.201400337