5-bromo-1-isopropyl-1H-indole-3-carbaldehyde

Base Information

Chemical Name:5-bromo-1-isopropyl-1H-indole-3-carbaldehyde
CAS No.:593235-95-1
Molecular Formula:C12H12BrNO
Molecular Weight:266.137
Hs Code.:
DSSTox Substance ID:DTXSID901217011
Mol file:593235-95-1.mol

Synonyms:5-bromo-1-isopropyl-1H-indole-3-carbaldehyde;593235-95-1;5-bromo-1-propan-2-ylindole-3-carbaldehyde;5-bromo-1-(propan-2-yl)-1H-indole-3-carbaldehyde;SCHEMBL671605;IGVNOZSHNDWZRN-UHFFFAOYSA-N;DTXSID901217011;AKOS000291184;FT-0712842;5-Bromo-1-(1-methylethyl)-1H-indole-3-carboxaldehyde

Suppliers and Price of 5-bromo-1-isopropyl-1H-indole-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 5-bromo-1-isopropyl-1H-indole-3-carbaldehyde

Chemical Property:

PSA：22.00000
LogP:3.79720
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:265.01023
Heavy Atom Count:15
Complexity:244

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N1C=C(C2=C1C=CC(=C2)Br)C=O

Technology Process of 5-bromo-1-isopropyl-1H-indole-3-carbaldehyde

There total 3 articles about 5-bromo-1-isopropyl-1H-indole-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-30-9
2-iodo-propane

: 877-03-2
5-bromo-1H-indole-3-carboxaldehyde

: 593235-95-1
5-bromo-1-isopropyl-1H-indole-3-carbaldehyde

Guidance literature:: 5-bromo-1H-indole-3-carboxaldehyde; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

2-iodo-propane; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

Reference yield:

: 877-03-2
5-bromo-1H-indole-3-carboxaldehyde

: 75-26-3
isopropyl bromide

: 593235-95-1
5-bromo-1-isopropyl-1H-indole-3-carbaldehyde

Guidance literature:: 5-bromo-1H-indole-3-carboxaldehyde; With sodium hydroxide; In water; dimethyl sulfoxide; at 20 ℃; for 0.25h;

isopropyl bromide; In water; dimethyl sulfoxide; Heating;
DOI:10.1007/s11094-020-02215-w

Reference yield:

: 10075-50-0
5-bromo-1H-indole

: 593235-95-1
5-bromo-1-isopropyl-1H-indole-3-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 0 °C

1.2: 1 h / Heating

2.1: sodium hydroxide / dimethyl sulfoxide; water / 0.25 h / 20 °C

2.2: Heating

With sodium hydroxide; trichlorophosphate; In water; dimethyl sulfoxide; 1.1: |Vilsmeier-Haack Formylation / 1.2: |Vilsmeier-Haack Formylation;
DOI:10.1007/s11094-020-02215-w