4-(1,3-Thiazol-2-yl)benzonitrile

Base Information

Chemical Name:4-(1,3-Thiazol-2-yl)benzonitrile
CAS No.:672324-84-4
Molecular Formula:C10H6N2S
Molecular Weight:186.237
Hs Code.:2934100090
DSSTox Substance ID:DTXSID10441026
Wikidata:Q82257565
Mol file:672324-84-4.mol

Synonyms:4-(Thiazol-2-yl)benzonitrile;672324-84-4;4-(1,3-thiazol-2-yl)benzonitrile;4-Thiazol-2-yl-benzonitrile;SCHEMBL2225287;DTXSID10441026;MFCD09025835;AKOS006282774;AS-6415;CS-0268160;FT-0758677;EN300-745794;A846587;J-513874

Suppliers and Price of 4-(1,3-Thiazol-2-yl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Thiazol-2-yl)benzonitrile
50mg
$ 45.00

Crysdot
4-(Thiazol-2-yl)benzonitrile 95+%
5g
$ 377.00

Chemenu
4-(thiazol-2-yl)benzonitrile 95%
5g
$ 356.00

American Custom Chemicals Corporation
4-(1,3-THIAZOL-2-YL)BENZONITRILE 95.00%
5G
$ 1369.20

American Custom Chemicals Corporation
4-(1,3-THIAZOL-2-YL)BENZONITRILE 95.00%
1G
$ 753.12

Alichem
4-(Thiazol-2-yl)benzonitrile
5g
$ 335.72

Advanced Chemicals Intermediatesced Chemicals Intermediates
4-Thiazol-2-yl-benzonitrile 95%+
10g
$ 855.50

Acints
4-Thiazol-2-yl-benzonitrile 95%+
10g
$ 855.50

Total 8 raw suppliers

Chemical Property of 4-(1,3-Thiazol-2-yl)benzonitrile

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.646
Boiling Point:356.937°C at 760 mmHg
Flash Point:169.67°C
PSA：64.92000
Density:1.3g/cm³
LogP:2.68178
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:186.02516937
Heavy Atom Count:13
Complexity:212

Purity/Quality:

97% ^*data from raw suppliers

4-(Thiazol-2-yl)benzonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C#N)C2=NC=CS2

Technology Process of 4-(1,3-Thiazol-2-yl)benzonitrile

There total 6 articles about 4-(1,3-Thiazol-2-yl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 288-47-1
1,3-thiazole

: 623-03-0
4-Cyanochlorobenzene

: 672324-84-4
4-(thiazol-2-yl)benzonitrile

Guidance literature:: 1,3-thiazole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

With zinc(II) chloride; In tetrahydrofuran; at -78 - 20 ℃; for 1.5h; Inert atmosphere;

4-Cyanochlorobenzene; With dichloro(1,3-bis(2,6-bis(3-pentyl)phenyl)imidazolin-2-ylidene)(3-chloropyridyl)palladium(II); In tetrahydrofuran; at 60 ℃; for 24h; Inert atmosphere;
DOI:10.1002/anie.200906811

Reference yield: 90.0%

: 4-(4,5-dihydrothiazol-2-yl)benzonitrile

: 672324-84-4
4-(thiazol-2-yl)benzonitrile

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 20 ℃; for 9h; Molecular sieve;
DOI:10.1002/asia.201300267

Reference yield: 89.0%

: 3034-53-5,215777-74-5
2-bromo-1,3-thiazole

: 126747-14-6
4-cyanophenylboronic acid

: 672324-84-4
4-(thiazol-2-yl)benzonitrile

Guidance literature:: With sodium carbonate; palladium triphenylphosphine; In water; acetonitrile; at 90 ℃; for 24h; Inert atmosphere; Sealed tube;