1-(2-Amino-6-chlorophenyl)-2-chloroethan-1-one

Base Information

Chemical Name:1-(2-Amino-6-chlorophenyl)-2-chloroethan-1-one
CAS No.:64605-39-6
Molecular Formula:C8H7 Cl2 N O
Molecular Weight:204.05328
Hs Code.:2922399090
DSSTox Substance ID:DTXSID70499765
Wikidata:Q82350833

Synonyms:64605-39-6;ETHANONE, 1-(2-AMINO-6-CHLOROPHENYL)-2-CHLORO- (9CI);1-(2-Amino-6-chlorophenyl)-2-chloroethan-1-one;SCHEMBL11457421;DTXSID70499765

Suppliers and Price of 1-(2-Amino-6-chlorophenyl)-2-chloroethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(2-Amino-6-chlorophenyl)-2-chloroethan-1-one

Chemical Property:

Melting Point:50.5-52 °C
Boiling Point:310.7±27.0 °C(Predicted)
PKA:-0.99±0.10(Predicted)
PSA：43.09000
Density:1.392±0.06 g/cm3(Predicted)
LogP:2.92490
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:202.9904692
Heavy Atom Count:12
Complexity:174

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)Cl)C(=O)CCl)N

Technology Process of 1-(2-Amino-6-chlorophenyl)-2-chloroethan-1-one

There total 3 articles about 1-(2-Amino-6-chlorophenyl)-2-chloroethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 68095-21-6
N-[3-Chloro-2-(2-chloro-acetyl)-phenyl]-acetamide

: 64605-39-6
6-chloro-2-amino-α-chloroacetophenone

Guidance literature:: N-[3-Chloro-2-(2-chloro-acetyl)-phenyl]-acetamide; With hydrogenchloride; water; In ethanol; for 1.25h; Reflux;

With sodium hydroxide; In ethanol; water; pH=Ca. 9;
DOI:10.1016/j.bmc.2010.06.040

Reference yield:

: 107-14-2
chloroacetonitrile

: 108-42-9
3-chloro-aniline

: 64605-37-4
1-(2-amino-4-chlorophenyl)-2-chloroethan-1-one

: 64605-39-6
6-chloro-2-amino-α-chloroacetophenone

Guidance literature:: With aluminum (III) chloride; boron trichloride - methyl sulfide complex; In 1,2-dichloro-ethane;
DOI:10.1016/j.bmc.2010.06.040