Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Base Information

Chemical Name:Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
CAS No.:144060-96-8
Molecular Formula:C17H20BrNO3S
Molecular Weight:398.321
Hs Code.:2934100090
DSSTox Substance ID:DTXSID20447039
Wikidata:Q72473247
Mol file:144060-96-8.mol

Synonyms:144060-96-8;ETHYL 2-(3-BROMO-4-ISOBUTOXYPHENYL)-4-METHYL-5-THIAZOLECARBOXYLATE;Ethyl 2-[3-bromo-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylate;Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate;ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate;Ethyl2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate;SCHEMBL455907;DTXSID20447039;BCP23104;AKOS015900467;CS-0446647;FT-0686936;Q-103510;Ethyl 2-(3-bromo-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylate;2-(3-bromo-4-isobutoxy-phenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95+%
250mg
$ 416.00

Matrix Scientific
Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95+%
1g
$ 924.00

Crysdot
Ethyl2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95+%
1g
$ 432.00

American Custom Chemicals Corporation
ETHYL 2-(3-BROMO-4-ISOBUTOXYPHENYL)-4-METHYL-5-THIAZOLECARBOXYLATE 95.00%
5MG
$ 499.06

Alichem
Ethyl2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
1g
$ 344.96

AK Scientific
Ethyl2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
1g
$ 1297.00

Total 49 raw suppliers

Chemical Property of Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Chemical Property:

Vapor Pressure:3.02E-09mmHg at 25°C
Refractive Index:1.562
Boiling Point:476.5 °C at 760 mmHg
Flash Point:242 °C
PSA：76.66000
Density:1.335 g/cm³
LogP:5.09250
Storage Temp.:2-8°C
XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:397.03473
Heavy Atom Count:23
Complexity:396

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N=C(S1)C2=CC(=C(C=C2)OCC(C)C)Br)C

Technology Process of Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

There total 5 articles about Ethyl 2-(3-bromo-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 208665-96-7
3-bromo-4-isobutoxyphenylthiocarboxamide

: 609-15-4
ethyl 2-chloro-3-oxo-butyrate

: 144060-96-8
2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

Guidance literature:: In ethanol; for 16h; Reflux; Inert atmosphere;

Reference yield: 73.2%

: 144060-79-7
2-(3-bromo-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

: 78-77-3
Isobutyl bromide

: 144060-96-8
2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 - 85 ℃; for 5h;

Reference yield:

: 2973-78-6
3-bromo-4-hydroxybenzylaldehyde

: 144060-96-8
2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydroxylamine hydrochloride; sodium formate; formic acid / 5 h / 105 - 110 °C

2.1: hydrogenchloride / isopropyl alcohol / 0.25 h

2.2: 2 h / 50 - 55 °C

3.1: isopropyl alcohol / 5 h / 80 - 85 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 80 - 85 °C

With hydrogenchloride; formic acid; hydroxylamine hydrochloride; sodium formate; potassium carbonate; In N,N-dimethyl-formamide; isopropyl alcohol;