4-METHOXY-2-CHLOROANILINE

Base Information

• Chemical Name: 4-METHOXY-2-CHLOROANILINE
• CAS No.: 29242-84-0
• Molecular Formula: C7H8ClNO
• Molecular Weight: 157.6
• Hs Code.: 2922299090
• Mol file: 29242-84-0.mol

Synonyms:p-Anisidine,2-chloro- (8CI);2-Chloro-4-methoxyaniline;2-Chloro-4-methoxybenzenamine;2-Chloro-p-anisidine;4-Methoxy-2-chloroaniline;

Chemical Property of 4-METHOXY-2-CHLOROANILINE

Chemical Property:

• Vapor Pressure: 0.00222mmHg at 25°C
• Melting Point: 114℃
• Boiling Point: 249.2 °C at 760 mmHg
• PKA: 3.26±0.10(Predicted)
• Flash Point: 104.5 °C
• PSA: 35.25000
• Density: 1.234 g/cm³
• LogP: 2.51200
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-4-methoxyaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-METHOXY-2-CHLOROANILINE

There total 15 articles about 4-METHOXY-2-CHLOROANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-chloro-4-nitroanisole (28987-59-9) → 2-chloro-4-methoxyaniline (29242-84-0)

Guidance literature:

With ammonium chloride; zinc; In methanol; at 20 ℃; for 1h;

Reference yield: 100.0%

N-(2-chloro-4-methoxyphenyl)acetamide (31601-42-0) → 2-chloro-4-methoxyaniline (29242-84-0)

Guidance literature:

With sodium hydroxide; In ethanol; at 50 ℃; for 72h; Heating / reflux;

Reference yield: 65.0%

2-chloro-4-methoxyazobenzene → 2-chloro-4-methoxyaniline (29242-84-0)

Guidance literature:

With hydrogen; In isopropyl alcohol; at 60 ℃; for 1h; under 15001.5 Torr; Autoclave;

DOI:10.1134/S1070363216100121

upstream raw materials:

para-methoxynitrobenzene

N,N'-bis(4-methoxyphenyl)urea

3-chloro-4-nitroanisole

hydrogenchloride

Downstream raw materials:

3-chloro-4-nitroso-anisole

N-(2-chloro-4-methoxyphenyl)acetamide

N-(2-chloro-4-methoxyphenyl)benzamide

2-chloro-4-methoxy-4'-methylstilbene