2-Amino-4-hydroxy-3-methylbenzonitrile

Base Information

Chemical Name:2-Amino-4-hydroxy-3-methylbenzonitrile
CAS No.:102569-26-6
Molecular Formula:C8H8 N2 O
Molecular Weight:148.164
Hs Code.:2926907090
DSSTox Substance ID:DTXSID10541499
Wikidata:Q82417870
Mol file:102569-26-6.mol

Synonyms:2-amino-4-hydroxy-3-methylbenzonitrile;102569-26-6;Benzonitrile, 2-amino-4-hydroxy-3-methyl-;SCHEMBL998935;DTXSID10541499;NTRYGFSYGXKOSE-UHFFFAOYSA-N;CEA56926;CS-M0645;AKOS006374059;CS-13574

Suppliers and Price of 2-Amino-4-hydroxy-3-methylbenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Amino-4-hydroxy-3-methylbenzonitrile, technical grade tech%
250 mg
$ 1552.00

ChemScene
2-Amino-4-hydroxy-3-methylbenzonitrile
100mg
$ 311.00

Apolloscientific
2-Amino-4-hydroxy-3-methylbenzonitrile
250mg
$ 1310.00

American Custom Chemicals Corporation
2-AMINO-4-HYDROXY-3-METHYLBENZONITRILE 95.00%
5MG
$ 504.71

Total 12 raw suppliers

Chemical Property of 2-Amino-4-hydroxy-3-methylbenzonitrile

Chemical Property:

PSA：70.04000
LogP:1.73568
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:148.063662883
Heavy Atom Count:11
Complexity:184

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-4-hydroxy-3-methylbenzonitrile, technical grade tech% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1N)C#N)O

Technology Process of 2-Amino-4-hydroxy-3-methylbenzonitrile

There total 2 articles about 2-Amino-4-hydroxy-3-methylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 72817-94-8
4-amino-5-cyano-2-hydroxy-3-methylbenzoic acid

: 102569-26-6
2-amino-4-hydroxy-3-methylbenzonitrile

Guidance literature:: With quinoline; at 170 ℃; for 2h;

Reference yield:

: 72817-85-7
4-Amino-5-cyan-3-methyl-salicylsaeure-ethylester

: 102569-26-6
2-amino-4-hydroxy-3-methylbenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hydroxide; ethanol; water / 4 h / 20 - 80 °C

1.2: pH 5

2.1: quinoline / 2 h / 170 °C

With lithium hydroxide; ethanol; water; In quinoline;

Reference yield: 93.0%

: 102569-26-6
2-amino-4-hydroxy-3-methylbenzonitrile

: 74-88-4
methyl iodide

: 923274-68-4
2-amino-4-methoxy-3-methylbenzonitrile

Guidance literature:: 2-amino-4-hydroxy-3-methylbenzonitrile; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 4h;