1-Adamantylacrylate

Base Information

• Chemical Name: 1-Adamantylacrylate
• CAS No.: 121601-93-2
• Molecular Formula: C13H18O2
• Molecular Weight: 206.28
• Hs Code.: 2902190000
• Mol file: 121601-93-2.mol

Synonyms:2-Propenoicacid, tricyclo[3.3.1.13,7]dec-1-yl ester;Adamantan-1-yl acrylate;

Chemical Property of 1-Adamantylacrylate

Chemical Property:

• Melting Point: 39 °C
• Boiling Point: 272.133 °C at 760 mmHg
• Flash Point: 108.495 °C
• PSA: 26.30000
• Density: 1.09 g/cm³
• LogP: 2.68440
• Storage Temp.: 2-8°C
• Solubility.: soluble in Methanol

Purity/Quality:

Adamantan-1-yl Acrylate (stabilized with BHT) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Adamantylacrylate

There total 8 articles about 1-Adamantylacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acrylic acid anhydride (2051-76-5) + 1-adamanthanol (768-95-6) → 1-acryloyloxy-adamantane (121601-93-2)

Guidance literature:

Acidic catalyst; In cyclohexane; Heating;

Reference yield: 95.0%

1-adamanthanol (768-95-6) + acrylic acid (79-10-7) → 1-acryloyloxy-adamantane (121601-93-2)

Guidance literature:

Acidic catalyst; In cyclohexane; Heating;

Reference yield: 90.0%

1-adamanthanol (768-95-6) + acryloyl chloride (814-68-6,25189-84-8) → 1-acryloyloxy-adamantane (121601-93-2)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃;

DOI:10.1021/jo005747m

upstream raw materials:

acrylic acid anhydride

1-adamanthanol

acrylic acid

1-(2-propenyloxy)tricyclo<3.3.1.1^3,7>decane

Downstream raw materials:

(+/-)-(2S^*,4S^*,5R^*)-tetrahydro-4-(carbo-1-adamantoxy)-2-phenyl-5-vinylfuran

(+/-)-(2S^*,4R^*,5R^*)-tetrahydro-4-(carbo-1-admantoxy)-2-phenyl-5-vinylfuran

C₃₅H₄₀F₆N₂O₅

C₃₅H₄₀F₆N₂O₅

Refernces

• 1、 Averina, Elena B.,Vasilenko, Dmitry A.,Gracheva, Yulia A.,Grishin, Yuri K.,Radchenko, Eugene V.,Burmistrov, Vladimir V.,Butov, Gennady M.,Neganova, Margarita E.,Serkova, Tatyana P.,Redkozubova, Olga M.,Shevtsova, Elena F.,Milaeva, Elena R.,Kuznetsova, Tamara S.,Zefirov, Nikolay S.. "Synthesis and biological evaluation of novel 5-hydroxylaminoisoxazole derivatives as lipoxygenase inhibitors and metabolism enhancing agents". . p. 712 - 720. Retrieved 2016.
• 2、 Woydziak, Zachary R.,Yucel, A. John,Chamberlin, A. Richard. "Tautomycetin Synthetic Analogues: Selective Inhibitors of Protein Phosphatase I". . p. 839 - 850. Retrieved 2020/12/15.
• 3、 Zhang, Jinquan,Zhang, Shuaizhong,Zou, Hongbin. "Acid- And base-switched palladium-catalyzed γ-C(sp3)-H alkylation and alkenylation of neopentylamine". supporting information. p. 3466 - 3471. Retrieved 2021/05/31.