3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid

Base Information

Chemical Name:3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid
CAS No.:184040-74-2
Molecular Formula:C9H7 Cl N2 O5 S2
Molecular Weight:322.74500
Hs Code.:2935009090
European Community (EC) Number:606-015-4
DSSTox Substance ID:DTXSID20445212
Wikidata:Q72454164
ChEMBL ID:CHEMBL67664
Mol file:184040-74-2.mol

Synonyms:184040-74-2;3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid;2-Thiophenecarboxylicacid, 3-[[(4-chloro-3-methyl-5-isoxazolyl)amino]sulfonyl]-;3-[(4-chloro-3-methyl-1,2-oxazol-5-yl)sulfamoyl]thiophene-2-carboxylic Acid;CHEMBL67664;3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)-thiophene-2-carboxylic acid;SCHEMBL2842500;DTXSID20445212;BCP12517;CS-M1004;BDBM50289942;MFCD18642943;3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid;AKOS015909969;A880798;[(4-chloro-3-methyl-1,2-oxazol-5-yl)sulfamoyl]thiophene-2-carboxylic acid;3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid;3-[(4-chloro-3-methyl-5-isoxazolyl)sulfamoyl]-2-thiophenecarboxylic acid;N-(4-chloro-3-methyl-5-isoxazolyl)-3-sulfamoyl-2-thiophenecarboxylic acid

Suppliers and Price of 3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicAcid
500mg
$ 130.00

Matrix Scientific
3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)-thiophene-2-carboxylic acid 95+%
250mg
$ 591.00

Matrix Scientific
3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)-thiophene-2-carboxylic acid 95+%
1g
$ 1311.00

Crysdot
3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid 97%
5g
$ 1664.00

Crysdot
3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid 97%
10g
$ 2822.00

Crysdot
3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid 97%
1g
$ 475.00

ChemScene
3-(N-(4-chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid
100mg
$ 171.00

ChemScene
3-(N-(4-chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid
250mg
$ 243.00

ChemScene
3-(N-(4-chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid
1g
$ 687.00

ChemScene
3-(N-(4-chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicacid
5g
$ 2276.00

Total 18 raw suppliers

Chemical Property of 3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:556.983oC at 760 mmHg
Flash Point:290.653oC
PSA：146.12000
Density:1.746g/cm3
LogP:3.35070
Storage Temp.:2-8°C(protect from light)
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:321.9484914
Heavy Atom Count:19
Complexity:454

Purity/Quality:

97% ^*data from raw suppliers

3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NOC(=C1Cl)NS(=O)(=O)C2=C(SC=C2)C(=O)O

Technology Process of 3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid

There total 2 articles about 3-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 184644-72-2
3-{[(4-chloro-3-methyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxylic acid methyl ester

: 184040-74-2
3{[(4-chloro-3-methyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxylic acid

Guidance literature:

Reference yield:

: 59337-92-7
2-(carbomethoxy)thiophene-3-sulfonyl chloride

: 184040-74-2
3{[(4-chloro-3-methyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / 1 h / Ambient temperature

2: aq. NaOH / 8 h / Ambient temperature

With sodium hydroxide; sodium hydride; In tetrahydrofuran;
DOI:10.1016/S0960-894X(97)00367-3