6-[(2-AMINOETHYL)AMINO]NICOTINONITRILE

Base Information

• Chemical Name: 6-[(2-AMINOETHYL)AMINO]NICOTINONITRILE
• CAS No.: 202460-48-8
• Molecular Formula: C8H10 N4
• Molecular Weight: 162.194
• Mol file: 202460-48-8.mol

Synonyms:2-(2-Aminoethylamino)-5-cyanopyridine;6-(2-Aminoethylamino)nicotinonitrile; 6-[(2-Aminoethyl)amino]pyridine-3-carbonitrile

Chemical Property of 6-[(2-AMINOETHYL)AMINO]NICOTINONITRILE

Chemical Property:

• PSA: 74.73000
• LogP: 1.09718

Purity/Quality:

99% ^*data from raw suppliers

6-[(2-AMINOETHYL)AMINO]NICOTINONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-[(2-AMINOETHYL)AMINO]NICOTINONITRILE

There total 3 articles about 6-[(2-AMINOETHYL)AMINO]NICOTINONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

6-chloronicotinonitrile (33252-28-7) + ethylenediamine (107-15-3,85404-18-8) → 6-[(2-aminoethyl)amino]pyridine-3-carbonitrile (202460-48-8)

Guidance literature:

With potassium carbonate; at 20 ℃; for 3h;

Reference yield: 78.0%

6-chloronicotinonitrile (33252-28-7) → 6-[(2-aminoethyl)amino]pyridine-3-carbonitrile (202460-48-8)

Guidance literature:

In methanol; ethyl acetate; ethylenediamine; acetonitrile;

Reference yield:

→ 6-[(2-aminoethyl)amino]pyridine-3-carbonitrile (202460-48-8)

Guidance literature:

upstream raw materials:

6-chloronicotinonitrile

ethylenediamine

Downstream raw materials:

(S)-1-{2-[(5-cyanopyridin-2-yl)amino]ethyl-aminoacetyl}-2-cyano-pyrrolidine

KR-62436

6-{2-[2-(2-Trifluoromethyl-phenyl)-5,6,7,8-tetrahydro-quinazolin-4-ylamino]-ethylamino}-nicotinonitrile

6-{2-[2-(2,4-Dichloro-phenyl)-quinazolin-4-ylamino]-ethylamino}-nicotinonitrile

Refernces

• 1、 -. "COMPOUNDS AND METHODS". Page/Page column 44; 45. . Retrieved 2013/03/26.
• 2、 -. "PYRAZOLE COMPOUND". Page/Page column 46-47. . Retrieved 2010/11/28.