2-(4-Methoxyphenyl)pyrazine

Base Information

Chemical Name:2-(4-Methoxyphenyl)pyrazine
CAS No.:108030-81-5
Molecular Formula:C11H10 N2 O
Molecular Weight:186.213
Hs Code.:
DSSTox Substance ID:DTXSID50460837
Nikkaji Number:J2.254.075K
Wikidata:Q82284988

Synonyms:2-(4-methoxyphenyl)pyrazine;108030-81-5;SCHEMBL4907132;Pyrazine,2-(4-methoxyphenyl)-;DTXSID50460837;HOHBZVISTUFMRA-UHFFFAOYSA-N;AKOS015909647

Suppliers and Price of 2-(4-Methoxyphenyl)pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 2-(4-Methoxyphenyl)pyrazine

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:186.079312947
Heavy Atom Count:14
Complexity:167

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC=CN=C2

Technology Process of 2-(4-Methoxyphenyl)pyrazine

There total 27 articles about 2-(4-Methoxyphenyl)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 14508-49-7
2-chloropyrazin

: 5720-07-0
4-methoxyphenylboronic acid

: 108030-81-5
2-(4-methoxyphenyl)pyrazine

Guidance literature:: With palladium diacetate; potassium carbonate; triphenylphosphine; In 1,2-dimethoxyethane; at 100 ℃; for 5h;
DOI:10.1021/jm020557k

Reference yield: 95.0%

: 5720-07-0
4-methoxyphenylboronic acid

: 32111-21-0
2-iodopyrazine

: 108030-81-5
2-(4-methoxyphenyl)pyrazine

Guidance literature:: With potassium carbonate; In ethanol; water; at 90 ℃; for 0.5h; Microwave irradiation;
DOI:10.1021/jo500409r

Reference yield: 90.0%

: 290-37-9
1,4-pyrazine

: 696-62-8
para-iodoanisole

: 108030-81-5
2-(4-methoxyphenyl)pyrazine

Guidance literature:: With potassium tert-butylate; toluene-4-sulfonic acid hydrazide; at 135 ℃; for 24h; regioselective reaction; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1021/ol502370r