5-Oxopiperidine-2-carboxylic acid

Base Information

• Chemical Name: 5-Oxopiperidine-2-carboxylic acid
• CAS No.: 789448-80-2
• Molecular Formula: C₆H₉NO₃
• Molecular Weight: 143.142
• DSSTox Substance ID: DTXSID00586278
• Mol file: 789448-80-2.mol

Synonyms:5-OXOPIPERIDINE-2-CARBOXYLIC ACID;789448-80-2;5-OXO-PIPERIDINE-2-CARBOXYLIC ACID;(2R)-5-oxopiperidine-2-carboxylic acid;146467-21-2;1414960-63-6;5-oxopipecolic acid;SCHEMBL5928107;DTXSID00586278;YXHXRACVAHDTEL-UHFFFAOYSA-N;5-oxo-2-Piperidine carboxylic acid;MFCD19227688;AKOS006289052;SB12083;SB13906;SB13907;SY317752;DB-075528;CS-0055636;P10634;racemic (+/-)-5-oxopiperidine-2-carboxylic acid

Chemical Property of 5-Oxopiperidine-2-carboxylic acid

Chemical Property:

• Boiling Point: 345.955 °C at 760 mmHg
• Flash Point: 163.028 °C
• PSA: 66.40000
• Density: 1.287 g/cm³
• LogP: -0.27910
• XLogP3: -2.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 143.058243149
• Heavy Atom Count: 10
• Complexity: 166

Purity/Quality:

97% ^*data from raw suppliers

5-Oxo-piperidine-2-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(=O)CNC1C(=O)O

Technology Process of 5-Oxopiperidine-2-carboxylic acid

There total 8 articles about 5-Oxopiperidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

N-benzylpiperidine-5-one-2S-carboxylic acid → (S)-5-oxo-2-piperidinecarboxylic acid (146467-21-2,789448-80-2)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In methanol; at 40 - 45 ℃; for 5h; under 750.075 - 2250.23 Torr;

Reference yield: 97.9%

benzyl N-benzylpiperidine-5-one-2S-carboxylate → (S)-5-oxo-2-piperidinecarboxylic acid (146467-21-2,789448-80-2)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In methanol; at 40 - 45 ℃; for 6h; under 1500.15 - 2250.23 Torr;

Reference yield: 73.0%

6-diazo-5-oxo-L-norleucine (157-03-9,7390-76-3,764-17-0) → (S)-5-oxo-2-piperidinecarboxylic acid (146467-21-2,789448-80-2)

Guidance literature:

With Ru(CO)(TPPS); In water; at 25 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tet.2010.04.080

upstream raw materials:

N-ethoxycarbonylmethyl-N-benzoyl-L-glutamic acid diethyl ester

L-glutamic acid diethyl ester

6-diazo-5-oxo-L-norleucine

L-glutamic acid

Downstream raw materials:

(±)-1-tert-butoxycarbonyl-5-oxopiperidine-2-carboxylic acid

(2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 789448-80-2 5-oxopiperidine-2-carboxylic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send