(chlromethyl)dimethyl(phenyl)germane

Base Information

• Chemical Name: (chlromethyl)dimethyl(phenyl)germane
• CAS No.: 24486-57-5
• Molecular Formula: C₉H₁₃ClGe
• Molecular Weight: 229.245
• Mol file: 24486-57-5.mol

Synonyms:

Chemical Property of (chlromethyl)dimethyl(phenyl)germane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (chlromethyl)dimethyl(phenyl)germane

There total 3 articles about (chlromethyl)dimethyl(phenyl)germane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dibromo(chloromethyl)phenylgermane + bromochloro(chloromethyl)phenylgermane + methyllithium (917-54-4) + dichloro(chloromethyl)phenylgermane (19089-97-5) → (chlromethyl)dimethyl(phenyl)germane (24486-57-5)

Guidance literature:

In diethyl ether; under N2; a stirred soln. of the Ge compds. in (CH3CH2)2O was treated dropwise at -70°C within 2 h with a soln. of LiCH3 in (CH3CH2)2O, the mixt. was stirred for 4 h, the soln. was warmed to 25°C within 6 h; H2O was added, the aq. phase was extd. with (CH3CH2)2O, dried over Na2SO4, the solvent was removed in vac., the residue was distd. in vac.; elem. anal.;

DOI:10.1021/om000169l

Reference yield:

methyllithium (917-54-4) + dichloro(chloromethyl)phenylgermane (19089-97-5) → chloro(chloromethyl)methylphenylgermane (134317-77-4) + (chlromethyl)dimethyl(phenyl)germane (24486-57-5)

Guidance literature:

In diethyl ether; to a soln. of Ge-compd. in diethyl ether is added an etheral soln. of MeLi at -70°C during 2 h with stirring, then mixt. is allowed to warm to room temp. and stirred for 2 h under reflux (N2); ppt. is filtd. off and washed with petroleum ether, filtrate is evapd. to dryness (reduced pressure), residue is distd. in vac. (Vigreux column; 114-126°C/15 Torr), elem. anal.;

Reference yield:

→ (chlromethyl)dimethyl(phenyl)germane (24486-57-5)

Guidance literature:

C6H5MgBr, Chlorogerman III;

upstream raw materials:

methyllithium

dichloro(chloromethyl)phenylgermane

Downstream raw materials:

rac-2-amino-3-(dimethyl(phenyl)germyl)propionic acid ethyl ester

acetoxy(acetoxymethyl)methylphenylgermane