4-Chloro-8-methyl-2-(trifluoromethyl)quinoline

Base Information

Chemical Name:4-Chloro-8-methyl-2-(trifluoromethyl)quinoline
CAS No.:1701-25-3
Molecular Formula:C11H7 Cl F3 N
Molecular Weight:245.62800
Hs Code.:2933499090
DSSTox Substance ID:DTXSID90575954
Wikidata:Q72455513
Mol file:1701-25-3.mol

Synonyms:4-CHLORO-8-METHYL-2-(TRIFLUOROMETHYL)QUINOLINE;1701-25-3;SCHEMBL2711191;DTXSID90575954;UTYTYFOXVYEJRI-UHFFFAOYSA-N;MFCD08448258;AKOS009866965;AS-8922;SB69125;CS-0159076;G74596

Suppliers and Price of 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline
250mg
$ 75.00

SynQuest Laboratories
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline
5 g
$ 400.00

SynQuest Laboratories
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline
1 g
$ 141.00

Matrix Scientific
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline
5g
$ 1103.00

Matrix Scientific
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline
1g
$ 322.00

Crysdot
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline 95+%
5g
$ 339.00

Crysdot
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline 95+%
10g
$ 564.00

Chemenu
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline 95%
10g
$ 533.00

Chemenu
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline 95%
5g
$ 320.00

Apolloscientific
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline
5g
$ 250.00

Total 22 raw suppliers

Chemical Property of 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline

Chemical Property:

Vapor Pressure:0.022mmHg at 25°C
Melting Point:71-73 °C
Boiling Point:258oC
PKA:-1.18±0.50(Predicted)
Flash Point:110 ºC
PSA：12.89000
Density:1.376
LogP:4.21540
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:245.0219114
Heavy Atom Count:16
Complexity:256

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloro-8-methyl-2-(trifluoromethyl)quinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)C(=CC(=N2)C(F)(F)F)Cl

Technology Process of 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline

There total 4 articles about 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1701-19-5
8-methyl-2-trifluoromethyl-4-quinolinol

: 144-55-8
sodium hydrogencarbonate

: 1701-25-3
4-chloro-8-methyl-2-trifluoromethyl-quinoline

Guidance literature:: In trichlorophosphate;

Reference yield:

: 95-53-4
o-toluidine

: 1701-25-3
4-chloro-8-methyl-2-trifluoromethyl-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: polyphosphoric acid / 150 °C

2: trichlorophosphate / Reflux

With trichlorophosphate;
DOI:10.1039/c8ce00094h