(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one

Base Information

Chemical Name:(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one
CAS No.:272778-13-9
Molecular Formula:C₃₀H₃₇F₂NO₃Si₂
Molecular Weight:553.796
Hs Code.:
UNII:F66GW6P7TY
Mol file:272778-13-9.mol

Synonyms:272778-13-9;(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one;(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl-3-(trimethylsilyloxy)propyl)-4-(4-(trimethylsilyloxy)phenyl)azetidin-2-one;2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-[(trimethylsilyl)oxy]propyl]-4-[4-[(trimethylsilyl)oxy]phenyl]-, (3R,4S)-;(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)-oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one;(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-trimethylsilyloxypropyl]-4-(4-trimethylsilyloxyphenyl)azetidin-2-one;CID 11387325;F66GW6P7TY;3-{5-(4-Fluoro-phenyl)-2-[(4-fluoro-phenylamino)-(4-trimethylsilanyloxy-phenyl)-methyl]-5-trimethylsilanyloxy-pentanoyl}-4-phenyl-oxazolidin-2-one;SCHEMBL10108874;AMY19267;AKOS015999504;I11728;A818990;(3R, 4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-trimethylsilyloxypropyl]-4-(4-trimethylsilyloxyphenyl)azetidin-2-one;(3r,4s)-1-(4-fluorophenyl)-3-((s)-3-(4-fluorophenyl)-3-((trimethyl silyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one;(3R,4S)-1-(4-FLUOROPHENYL)-3-((S)-3-(4-FLUOROPHENYL)-3-(TRIMETHYLSILYLOXY)PROPYL)-4-(4-(TRIMETHYLSILYLOXY)PHENYL)AZETIDIN-2-ONE;(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-[(trimethylsilyl)oxy]propyl]-4-[4-[(trimethylsilyl)oxy]phenyl]-2-azetidinone

Suppliers and Price of (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)-oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one 95+%
250mg
$ 446.00

Matrix Scientific
(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)-oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one 95+%
1g
$ 975.00

Crysdot
(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one 95+%
1g
$ 460.00

American Custom Chemicals Corporation
(3R,4S)-1-(4-FLUOROPHENYL)-3-((S)-3-(4-FLUOROPHENYL-3-(TRIMETHYLSILYLOXY)PROPYL)-4-(4-(TRIMETHYLSILYLOXY)PHENYL)AZETIDIN-2-ONE 95.00%
250MG
$ 773.85

Alichem
(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one
1g
$ 368.28

Total 43 raw suppliers

Chemical Property of (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one

Chemical Property:

PSA：38.77000
Density:1.118
LogP:8.32060
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:553.22800344
Heavy Atom Count:38
Complexity:764

Purity/Quality:

98%, ^*data from raw suppliers

(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)-oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[Si](C)(C)OC1=CC=C(C=C1)C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O[Si](C)(C)C
Isomeric SMILES:C[Si](C)(C)OC1=CC=C(C=C1)[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O[Si](C)(C)C

Technology Process of (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one

There total 15 articles about (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.8%

: C₁₈H₂₀FNO₂Si

: C₁₂H₁₈ClFOSi

: 272778-13-9
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-(trimethylsilyloxy)propanyl)-4-(4-(trimethylsiloxy)phenyl)azetidinone

Guidance literature:: With lithium diisopropyl amide; In dimethyl sulfoxide; at 120 ℃; for 48h;

Reference yield: 79.0%

: 75-77-4
chloro-trimethyl-silane

: 870634-36-9
methyl 5S-5-(4-fluorophenyl)-5-hydroxyvalerate

: 3382-63-6,942485-62-3
N-(4-hydroxybenzylidene)-4-fluorobenzenamine

: 272778-13-9
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-(trimethylsilyloxy)propanyl)-4-(4-(trimethylsiloxy)phenyl)azetidinone

Guidance literature:: chloro-trimethyl-silane; methyl 5S-5-(4-fluorophenyl)-5-hydroxyvalerate; N-(4-hydroxybenzylidene)-4-fluorobenzenamine; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at -10 - 0 ℃; Inert atmosphere;

With (R,R)-(+)-N-benzyl-3,4-bis(diphenylphosphino)pyrrolidine; lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -10 - 0 ℃; Inert atmosphere;