2-(N-BOC-N-methylamino)-5-bromopyridine

Base Information

Chemical Name:2-(N-BOC-N-methylamino)-5-bromopyridine
CAS No.:227939-01-7
Molecular Formula:C11H15 Br N2 O2
Molecular Weight:287.15300
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80458469
Wikidata:Q82281747
Mol file:227939-01-7.mol

Synonyms:227939-01-7;2-(N-BOC-N-methylamino)-5-bromopyridine;tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate;tert-butyl N-(5-bromopyridin-2-yl)-N-methylcarbamate;(5-Bromopyridin-2-yl)methyl-carbamic acid tert-butyl ester;MFCD12546613;SCHEMBL1181429;DTXSID80458469;YHTZSPWLJTZRDM-UHFFFAOYSA-N;AKOS015892241;AM86779;CS-W003830;DS-0513;SY023794;FT-0648008;EN300-7351773;tert-butyl 5-bromopyridin-2-yl(methyl)carbamate;A878443;2-Methyl-2-propanyl (5-bromo-2-pyridinyl)methylcarbamate;5-Bromo-2-[N-(tert-butoxycarbonyl)-N-methylamino]pyridine;(5-bromo-pyridin-2-yl)-methyl-carbamic acid tert-butyl ester

Suppliers and Price of 2-(N-BOC-N-methylamino)-5-bromopyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(N-BOC-N-methylamino)-5-bromopyridine
500mg
$ 95.00

SynChem
2-(N-BOC-N-METHYLAMINO)-5-BROMOPYRIDINE 95%
1 g
$ 120.00

Matrix Scientific
(5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester 95+%
5g
$ 301.00

Matrix Scientific
(5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester 95+%
500mg
$ 64.00

Matrix Scientific
(5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester 95+%
250mg
$ 42.00

Matrix Scientific
(5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester 95+%
1g
$ 98.00

Crysdot
tert-Butyl(5-bromopyridin-2-yl)(methyl)carbamate 95+%
10g
$ 452.00

Crysdot
tert-Butyl(5-bromopyridin-2-yl)(methyl)carbamate 95+%
1g
$ 93.00

Crysdot
tert-Butyl(5-bromopyridin-2-yl)(methyl)carbamate 95+%
5g
$ 286.00

Chemenu
2-(N-Boc-N-methylamino)-5-bromopyridine 95%
5g
$ 270.00

Total 27 raw suppliers

Chemical Property of 2-(N-BOC-N-methylamino)-5-bromopyridine

Chemical Property:

Vapor Pressure:9.8E-05mmHg at 25°C
Boiling Point:338.5oC at 760 mmHg
Flash Point:158.5oC
PSA：51.22000
Density:1.391g/cm3
LogP:3.25970
Storage Temp.:2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:286.03169
Heavy Atom Count:16
Complexity:253

Purity/Quality:

97% ^*data from raw suppliers

2-(N-BOC-N-methylamino)-5-bromopyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N(C)C1=NC=C(C=C1)Br

Technology Process of 2-(N-BOC-N-methylamino)-5-bromopyridine

There total 5 articles about 2-(N-BOC-N-methylamino)-5-bromopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 84539-30-0
5-bromo-N-methylpyridin-2-amine

: 24424-99-5
di-tert-butyl dicarbonate

: 227939-01-7
5-bromo-2-(N-methyl-N-(t-butoxycarbonyl)amino)pyridine

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at 0 - 20 ℃; for 13h; Inert atmosphere;

Reference yield: 80.0%

: 74-88-4
methyl iodide

: 159451-66-8
tert-butyl N-(5-bromopyridin-2-yl)carbamate

: 227939-01-7
5-bromo-2-(N-methyl-N-(t-butoxycarbonyl)amino)pyridine

Guidance literature:: With sodium hydride; In tetrahydrofuran;
DOI:10.1002/jlcr.738

Reference yield:

: 1072-97-5
5-bromo-2-pyridylamine

: 227939-01-7
5-bromo-2-(N-methyl-N-(t-butoxycarbonyl)amino)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NaHMDS / tetrahydrofuran

2: 80 percent / NaH / tetrahydrofuran

With sodium hexamethyldisilazane; sodium hydride; In tetrahydrofuran;
DOI:10.1002/jlcr.738