METHYL 2-MERCAPTO-2-METHYL PROPIONATE

Base Information

• Chemical Name: METHYL 2-MERCAPTO-2-METHYL PROPIONATE
• CAS No.: 87123-08-8
• Molecular Formula: C₅H₁₀O₂S
• Molecular Weight: 134.199
• Hs Code.: 2930909090
• Mol file: 87123-08-8.mol

Synonyms:Propionicacid, 2-mercapto-2-methyl-, methyl ester (6CI)

Chemical Property of METHYL 2-MERCAPTO-2-METHYL PROPIONATE

Chemical Property:

• Vapor Pressure: 1.999mmHg at 25°C
• Boiling Point: 164.101oC at 760 mmHg
• PKA: 8.92±0.10(Predicted)
• Flash Point: 47.486oC
• PSA: 65.10000
• Density: 1.043g/cm3
• LogP: 0.86780
• Storage Temp.: -20°C Freezer
• Solubility.: Benzene, Chloroform, Ether, Ethyl Acetate,

Purity/Quality:

98%Min ^*data from raw suppliers

Methyl2-Mercapto-2-methylpropionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methyl 2-Mercapto-2-methylpropionate (cas# 87123-08-8) is a compound useful in organic synthesis.

Technology Process of METHYL 2-MERCAPTO-2-METHYL PROPIONATE

There total 5 articles about METHYL 2-MERCAPTO-2-METHYL PROPIONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methanol (67-56-1) + 2-mercapto-2-methylpropanoic acid (4695-31-2) → methyl 2-mercapto-2-methylpropanoate (87123-08-8)

Guidance literature:

With sulfuric acid; for 5h;

DOI:10.1021/jacs.7b11471

Reference yield: 93.0%

methanol (67-56-1) + 2-bromo-2-methylpropionic acid (2052-01-9) → methyl 2-mercapto-2-methylpropanoate (87123-08-8)

Guidance literature:

With sulfuric acid; for 5h;

Reference yield:

methyl 2-acetylmercapto-2-methylpropionate (99668-51-6,125833-32-1) → methyl 2-mercapto-2-methylpropanoate (87123-08-8)

Guidance literature:

With potassium hydroxide; In methanol; at 0 - 10 ℃;

upstream raw materials:

2-bromo-2-methylpropionic acid methyl ester

diazomethane

2-mercapto-2-methylpropanoic acid

methyl 2-acetylmercapto-2-methylpropionate

Downstream raw materials:

2-Benzylsulfanyl-2-methyl-propionic acid methyl ester