Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate

Base Information

Chemical Name:Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate
CAS No.:74272-77-8
Molecular Formula:C₁₂H₁₃NO₃
Molecular Weight:219.24
Hs Code.:
DSSTox Substance ID:DTXSID801197393

Synonyms:Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate;74272-77-8;SCHEMBL6751629;DTXSID801197393;FT-0772534;Methyl 4,5-dihydro-5-methyl-2-phenyl-4-oxazolecarboxylate;5-methyl-2-phenyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester;Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate #;5-Methyl-2-phenyl-4,5-dihydrooxazole-4-carboxylic acid, methyl ester

Suppliers and Price of Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:219.08954328
Heavy Atom Count:16
Complexity:295

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(N=C(O1)C2=CC=CC=C2)C(=O)OC

Technology Process of Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate

There total 10 articles about Methyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 3373-59-9
L-threonine methyl ester

: 5333-86-8
ethyl benzimidate hydrochloride

: 60538-17-2,62107-40-8,74272-77-8,79952-14-0,79952-15-1,82659-84-5,88336-08-7
(4S,5R)-4-methyl-2-phenyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1002/chem.200204649

Reference yield: 87.0%

: 79893-89-3
N-benzoyl-L-threonine methyl ester

: 60538-17-2,62107-40-8,74272-77-8,79952-14-0,79952-15-1,82659-84-5,88336-08-7
(4S,5R)-4-methyl-2-phenyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester

Guidance literature:: With tris(1,2-dioxyphenyl)cyclotriphosphazene; In toluene; at 120 ℃; for 12h; under 760.051 Torr; Inert atmosphere; Autoclave;
DOI:10.1021/acs.joc.1c02318