3,5-Difluoro-2-hydroxybenzoic acid

Base Information

Chemical Name:3,5-Difluoro-2-hydroxybenzoic acid
CAS No.:84376-20-5
Molecular Formula:C7H4F2O3
Molecular Weight:174.104
Hs Code.:2918290000
European Community (EC) Number:630-111-5
DSSTox Substance ID:DTXSID00447178
Nikkaji Number:J2.073.322E
Wikidata:Q82265999
Mol file:84376-20-5.mol

Synonyms:3,5-Difluoro-2-hydroxybenzoic acid;84376-20-5;3,5-Difluorosalicylic acid;MFCD06203609;3,5-difluoro-salicylic acid;3,5-difluoro-2-hydroxy-benzoic Acid;Benzoic acid, 3,5-difluoro-2-hydroxy-;SCHEMBL2791251;DTXSID00447178;GZPCNALAXFNOBT-UHFFFAOYSA-N;3,5-Difluoro-2-hydroxybenzoicacid;BBL101856;STL555653;AKOS005257469;CS-W017534;PS-8635;FT-0647526;EN300-725113;Z367679402

Suppliers and Price of 3,5-Difluoro-2-hydroxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,5-Difluoro-2-hydroxybenzoicAcid
100mg
$ 60.00

SynQuest Laboratories
3,5-Difluoro-2-hydroxybenzoic acid
1 g
$ 96.00

SynQuest Laboratories
3,5-Difluoro-2-hydroxybenzoic acid
5 g
$ 328.00

Crysdot
3,5-Difluoro-2-hydroxybenzoicacid 98%
5g
$ 314.00

Chemenu
3,5-Difluoro-2-hydroxybenzoicacid 95+%
5g
$ 297.00

Biosynth Carbosynth
3,5-Difluorosalicylic acid
2 g
$ 270.00

Biosynth Carbosynth
3,5-Difluorosalicylic acid
1 g
$ 180.00

Biosynth Carbosynth
3,5-Difluorosalicylic acid
5 g
$ 540.00

Biosynth Carbosynth
3,5-Difluorosalicylic acid
500 mg
$ 115.00

Biosynth Carbosynth
3,5-Difluorosalicylic acid
250 mg
$ 67.50

Total 17 raw suppliers

Chemical Property of 3,5-Difluoro-2-hydroxybenzoic acid

Chemical Property:

Vapor Pressure:0.0023mmHg at 25°C
Melting Point:188-189℃ (toluene )
Refractive Index:1.557
Boiling Point:276.6 °C at 760 mmHg
PKA:2.06±0.14(Predicted)
Flash Point:121.1 °C
PSA：57.53000
Density:1.6 g/cm³
LogP:1.36860
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:174.01285031
Heavy Atom Count:12
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

3,5-Difluoro-2-hydroxybenzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1C(=O)O)O)F)F

Technology Process of 3,5-Difluoro-2-hydroxybenzoic acid

There total 7 articles about 3,5-Difluoro-2-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 749230-36-2
4-chloro-3,5-difluoro-2-hydroxybenzoic acid

: 84376-20-5
3,5-difluoro-2-hydroxy-benzoic acid

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; at 25 ℃; for 20h;
DOI:10.1055/s-2004-829110

Reference yield: 73.1%

: 63954-77-8
3,5-difluorosalicylaldehyde

: 84376-20-5
3,5-difluoro-2-hydroxy-benzoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; aminosulfonic acid; sodium sulfite; In 1,4-dioxane; for 0.25h;
DOI:10.1080/00397919608004595