7-Chloroisoquinoline

Base Information

Chemical Name:7-Chloroisoquinoline
CAS No.:34784-06-0
Molecular Formula:C9H6ClN
Molecular Weight:163.60
Hs Code.:2933499090
European Community (EC) Number:636-430-6
DSSTox Substance ID:DTXSID10348824
Wikidata:Q72452859
Mol file:34784-06-0.mol

Synonyms:7-chloroisoquinoline;34784-06-0;isoquinoline, 7-chloro-;MFCD00094995;SCHEMBL691988;DTXSID10348824;AKOS006271855;CS-W007219;MB00648;DS-13166;SY065588;N,N-Dimethyl-1-(quinolin-2-yl)methanamine;FT-0709720;EN300-138751;J-519219;Z1198150534

Suppliers and Price of 7-Chloroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-chloroisoquinoline
10mg
$ 45.00

SynQuest Laboratories
7-Chloroisoquinoline
500 mg
$ 341.00

Sigma-Aldrich
7-CHLOROISOQUINOLINE Aldrich
250mg
$ 33.40

Matrix Scientific
7-Chloroisoquinoline
5g
$ 1080.00

Matrix Scientific
7-Chloroisoquinoline
10g
$ 1800.00

Matrix Scientific
7-Chloroisoquinoline
1g
$ 368.00

Crysdot
7-Chloroisoquinoline 98%
1g
$ 246.00

Crysdot
7-Chloroisoquinoline 98%
5g
$ 728.00

Chemenu
7-chloroisoquinoline 98%
5g
$ 688.00

Chemenu
7-chloroisoquinoline 98%
1g
$ 232.00

Total 35 raw suppliers

Chemical Property of 7-Chloroisoquinoline

Chemical Property:

Vapor Pressure:0.00382mmHg at 25°C
Melting Point:44-45 °C
Refractive Index:1.652
Boiling Point:289.5 °C at 760 mmHg
PKA:4.62±0.10(Predicted)
Flash Point:156.4 °C
PSA：12.89000
Density:1.271 g/cm³
LogP:2.88820
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:163.0188769
Heavy Atom Count:11
Complexity:138

Purity/Quality:

97% ^*data from raw suppliers

7-chloroisoquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC2=C1C=CN=C2)Cl
Uses 7-Chloroisoquinoline is used in preparation of 1H-1,2,3-triazole-5-carboxylic acid derivatives as glycolate oxidase inhibitors for treatment of hyperoxaluria and related diseases.

Technology Process of 7-Chloroisoquinoline

There total 10 articles about 7-Chloroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₉H₇ClO₂

: 34784-06-0
7-chloroisoquinoline

Guidance literature:: With ammonium hydroxide; In methanol; dichloromethane; at 20 ℃; for 24h;
DOI:10.1055/s-0037-1610223

Reference yield:

: 587-04-2
m-Chlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 34784-06-0
7-chloroisoquinoline

: 34784-07-1
8-chloroisoquinoline

Guidance literature:: m-Chlorobenzaldehyde; 2,2-dimethoxyethylamine; In toluene; Heating / reflux; Dean-Stark trap;

With sulfuric acid; at 140 ℃; for 0.333333h;

In water; pH=7;

Reference yield:

: 52085-98-0
6-chloroindan-1-ol

: 34784-06-0
7-chloroisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1.1: toluene-4-sulfonic acid / toluene / 1.5 h / 120 °C / Dean-Stark

2.1: ozone; oxygen / methanol; dichloromethane / 0.5 h / -78 - -65 °C / Inert atmosphere

2.2: 16 h / 20 °C / Inert atmosphere

3.1: ammonium hydroxide / dichloromethane; methanol / 24 h / 20 °C

With ammonium hydroxide; oxygen; toluene-4-sulfonic acid; ozone; In methanol; dichloromethane; toluene;
DOI:10.1055/s-0037-1610223