[(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester

Base Information

• Chemical Name: [(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester
• CAS No.: 312904-86-2
• Molecular Formula: C10H18N2O6
• Molecular Weight: 262.26000
• DSSTox Substance ID: DTXSID60432565
• Wikidata: Q82246637
• Mol file: 312904-86-2.mol

Synonyms:312904-86-2;[(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester;ethyl 2-[[2-(2,2-dimethoxyethylamino)-2-oxoacetyl]amino]acetate;SCHEMBL7211193;DTXSID60432565;BZVJOAISKWPBOF-UHFFFAOYSA-N;FT-0656635;A820789;Ethyl N-{[(2,2-dimethoxyethyl)amino](oxo)acetyl}glycinate;[(2,2-Dimethoxy-ethylaminooxalyl)-amino]-aceticacidethylester;Ethyl 2-{(N-(2,2-dimethoxyethyl)carbamoyl}carbonylamino)acetate;2-[[2-(2,2-dimethoxyethylamino)-1,2-dioxoethyl]amino]acetic acid ethyl ester;ethyl 2-[[2-(2,2-dimethoxyethylamino)-2-oxidanylidene-ethanoyl]amino]ethanoate

Chemical Property of [(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester

Chemical Property:

• PSA: 102.96000
• LogP: -0.81740
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 262.11648630
• Heavy Atom Count: 18
• Complexity: 290

Purity/Quality:

97% ^*data from raw suppliers

[(2,2-DIMETHOXY-ETHYLAMINOOXALYL)-AMINO]-ACETIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CNC(=O)C(=O)NCC(OC)OC

Technology Process of [(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester

There total 2 articles about [(2,2-Dimethoxy-ethylaminooxalyl)-amino]-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glycine ethyl ester hydrochloride (623-33-6) + Ethyl oxalyl chloride (4755-77-5) + 2,2-dimethoxyethylamine (22483-09-6) → N-(ethylcarboxymethyl)-N'-(2,2-dimethoxyethyl)oxamide (312904-86-2)

Guidance literature:

With potassium hydrogencarbonate; In Isopropyl acetate; water;

Reference yield:

[(2-ethoxy-2-oxoethyl)amino]oxoacetic acid ethyl ester (29655-79-6) + 2,2-dimethoxyethylamine (22483-09-6) → N-(ethylcarboxymethyl)-N'-(2,2-dimethoxyethyl)oxamide (312904-86-2)

Guidance literature:

In isopropyl alcohol; at 20 ℃;

DOI:10.1021/jm020311f

Reference yield: 73.0%

ethyl 2-{(N-(2,2-dimethoxyethyl)carbamoyl}carbonylamino acetate + N-(ethylcarboxymethyl)-N'-(2,2-dimethoxyethyl)oxamide (312904-86-2) → ethyl 3-hydroxypyrazin-(1H)-2-one-1-acetate (312904-87-3)

Guidance literature:

With acetic acid; trifluoroacetic acid; In ethyl acetate; toluene;

upstream raw materials:

[(2-ethoxy-2-oxoethyl)amino]oxoacetic acid ethyl ester

2,2-dimethoxyethylamine

glycine ethyl ester hydrochloride

Ethyl oxalyl chloride

Downstream raw materials:

ethyl 3-hydroxypyrazin-(1H)-2-one-1-acetate

ethyl 2-(3-chloro-2-oxopyrazin-1(2H)-yl)acetate