Technology Process of C34H39N7O4
There total 6 articles about C34H39N7O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C14H11N3O4; D-Phe-Lys(ε-Boc)-Rink-amide resin;
at 20 ℃;
for 16h;
Automated shaker;
solid phase reaction;
2-cyano-1-(4-methoxyphenyl)prop-2-en-1-yl acetate;
With
tert-butylimino-tri(pyrrolidino)phosphorane;
In
tetrahydrofuran;
at 20 ℃;
for 16h;
solid phase reaction;
With
triethylsilane; trifluoroacetic acid;
In
water;
solid phase reaction;
DOI:10.1021/ja203007u
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrazine hydrate / ethanol / 0 °C
2.1: dichloromethane / 1.75 h / 0 - 20 °C / Inert atmosphere
2.2: 0.33 h / 0 °C / Inert atmosphere
3.1: 16 h / 20 °C / Automated shaker; solid phase reaction
3.2: 16 h / 20 °C / solid phase reaction
3.3: solid phase reaction
With
hydrazine hydrate;
In
ethanol; dichloromethane;
3.2: Michael addition;
DOI:10.1021/ja203007u
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dichloromethane / 1.75 h / 0 - 20 °C / Inert atmosphere
1.2: 0.33 h / 0 °C / Inert atmosphere
2.1: 16 h / 20 °C / Automated shaker; solid phase reaction
2.2: 16 h / 20 °C / solid phase reaction
2.3: solid phase reaction
In
dichloromethane;
2.2: Michael addition;
DOI:10.1021/ja203007u
