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tert-butyl 1-(4-(4-bromophenyl)thiazol-2-yl)piperidin-4-ylcarbamate trifluoroacetate

Base Information
  • Chemical Name:tert-butyl 1-(4-(4-bromophenyl)thiazol-2-yl)piperidin-4-ylcarbamate trifluoroacetate
  • CAS No.:1341225-63-5
  • Molecular Formula:C2HF3O2*C19H24BrN3O2S
  • Molecular Weight:552.412
  • Hs Code.:
tert-butyl 1-(4-(4-bromophenyl)thiazol-2-yl)piperidin-4-ylcarbamate trifluoroacetate

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Chemical Property of tert-butyl 1-(4-(4-bromophenyl)thiazol-2-yl)piperidin-4-ylcarbamate trifluoroacetate
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Technology Process of tert-butyl 1-(4-(4-bromophenyl)thiazol-2-yl)piperidin-4-ylcarbamate trifluoroacetate

There total 2 articles about tert-butyl 1-(4-(4-bromophenyl)thiazol-2-yl)piperidin-4-ylcarbamate trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
tert-butyl 1-(4-bromothiazol-2-yl)piperidin-4-ylcarbamate; 4-Bromophenylboronic acid; With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In water; at 100 ℃; for 0.5h; Microwave irradiation;
trifluoroacetic acid; In water; acetonitrile;
DOI:10.1021/jm200497t
Guidance literature:
Multi-step reaction with 2 steps
1: triethylamine / 1,4-dioxane / 4 h / 100 - 120 °C / Microwave irradiation
2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water / 0.5 h / 100 °C / Microwave irradiation
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; triethylamine; In 1,4-dioxane; water; 2: Suzuki coupling;
DOI:10.1021/jm200497t
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